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Inosita Plus

Inosita Plus 50mg/500mg tablet

Brand: Pharm Evo

Prescription Prescription Required

generic
Inosita Plus 50mg/500mg tablet is composed of Sitagliptin (50mg)Metformin (500mg)

Sitagliptin is an oral anti-hyperglycemic medicine that belongs to the class of DPP-4 inhibitors. It is used to manage type II diabetes mellitus in adjunct to lifestyle changes. Diabetes is a chronic disease characterized by abnormally high levels of glucose in your blood. Type II diabetes is the most common form of diabetes where cells become resistant to insulin, leading to increased blood sugar. Sitagliptin increases the production of insulin and decreases the production of glucose.

Introduction

How To Use

  • Take this medicine by mouth with a glass of water.
  • Take this medicine with or without food, preferably with food.
  • Swallow it as a whole, do not crush or chew the medicine.
  • Take it at the same time to help you remember.
  • Or use it exactly as instructed by your doctor.

Expert Advice

  • Please take this medicine with or without meals.
  • Please consult your prescriber immediately if you experience trouble breathing, persistent abdominal pain, or any other adverse effects.
  • Dosage requires adjustment in case of trauma, surgery, and infection.
  • Please monitor glucose levels throughout use of this medicine.
  • Please ensure you tell your doctor you have diabetes before any surgery, getting medicine, etc.

 

Primary Uses

Type II diabetes

Indications

Monotherapy: This medicine is used for treating type 2 diabetes (condition characterized by elevated glucose levels) that is inadequately controlled by metformin, diet and exercise.

Dual therapy: It is used for treating diabetes type 2 along with metformin or a glitazone when patients respond inadequately to diet changes, exercise and either metformin or glitazine, or in combination with sulphonylureas in patients contraindicated for metformin, and for patients that do not respond adequately to sulphonylureas alone.

Triple therapy: This medicine is used with metformin and a sulphonylureas or glitazone for treating diabetes 2 that is inadequately controlled by dual therapy.

With insulin: This medicine is used with or without metformin for treating type 2 diabetes in patients who respond inadequately to diet, exercise, and insulin.

Side Effects

The patients administered with this medicine may experience pancreatitis (inflammation of pancreas), allergic reactions, Stevens-Jhonson Syndrome (allergic reaction), Hypoglycemia (low glucose levels), bullous pemphigoid (large fluid-filled blisters), osteoarthritis (weak bones), upper respiratory tract infections, flatulence, swelling, and influenza (flu-like symptoms). 

Warnings

Pregnancy

During pregnancy, Sitagliptin should be used only when clearly needed. Consult your doctor for more information.

Lactation

Sitagliptin should be used cautiously in nursing females. Consult your doctor for more information.

Driving

This medicine might affect your driving ability if your blood sugar levels become too low. Avoid driving until your glucose levels are controlled.

Liver

Sitagliptin is probably safe to use in liver patients. Consult your doctor for more information.

Kidney

Sitagliptin should be used cautiously in kidney patients. Dose adjustment might be required. Consult your doctor for more information.

Alcohol

Alcohol consumption should be avoided during the course of treatment. It is considered unsafe. Consult your doctor for more information.

Precautions

Before using this medicine, inform your doctor about your complete medical history; especially of pancreatitis, kidney disease, heart failure, and gallstones. Consult your doctor immediately if you develop symptoms of pancreatitis. Inform your doctor about all your current medicines. Do not quit this medicine without informing your doctor. Do not share this medicine with anyone. Do not double the dose, it may lead to severe hypoglycemia.

Contraindications

The patients with diabetic ketoacidosis (condition causing fat breakdown at an abnormal rate) and moderate to severe renal (kidney) impairment should avoid use of this medicine.

FAQS

Can this medicine cause low blood sugar?

This is a possible side effect, but can be avoided if meals are taken regularly. Try to carry sugar or a sugary drink in case you experience lightheadedness, or any other symptoms of low blood sugar. Take extra precautions during times of stress, or dehydration (fever, diarrhea etc.)

What do I do if I miss a dose?

You can take the missed dose as soon as you remember. If you remember when it is almost time for your next dose, then skip the missed dose entirely. Do not double your dose to catch up for missed doses.

What will happen if I skip a meal?

If you are not regular with your meals, you may experience symptoms of low blood sugar: Such as palpitation, sweating, dizziness, light headedness etc. In this case, taking sugar can relieve your symptoms.

Will this medicine make me gain or lose weight?

Weight gain is less likely with this drug.

Can this medicine cause disturbances in sleeping patterns, or stomach problems?

It is possible for patients to feel sleepy while taking this drug, and constipation is also a possible side effect.

What family of drugs does this medicine belong to?

Metformin belongs to a class of drugs known as biguanides. It is used to improve insulin activity, and control weight in diabetic patients. It is also known to regulate menstrual cycles (periods) and is used in the treatment of PCOs (Poly Cystic Ovarian Disease.)

Does this medicine contain hormones, or insulin?

No, this drug does not contain hormones, or insulin,. It enhances the effect of insulin, which helps patients with diabetes or PCOs, since their bodies tend to develop a resistance to the actions of insulin.

Can this drug be used with thyroid medications, and steroids?

Though there is no dangerous drug interaction, an adjustment in doses of both anti thyroid drugs, and steroids (eg: prednisone) may be required. It should be noted that patients taking steroids sometimes develop diabetes as a side effect. Please consult your physician, and discuss all the medicines you are taking, including their doses.

What is lactic acidosis and does this medication cause it?

Lactic acidosis is a very rare, and potentially fatal side effect of this medication. It occurs when there is an excessive buildup of lactic acid in the body. It may occur in patients who have overdosed. Symptoms include stomach problems, dizziness, breathing difficulty, muscle aches, irregular heartbeat, etc. Patients who experience these symptoms should go to a doctor immediately.

How long should I use this medicine for?

Please use this medicine for the time that has been prescribed, and in the dose prescribed by your physician. Using it for longer than prescribed can cause side effects such as Vitamin B12 deficiency.

Can this medicine cause low blood sugar?

Low blood sugar is rare with Metformin, but it is a possible side effect, especially if you are taking other anti-diabetic drugs. Please maintain regularity in meals, dosage, and exercise to maintain blood sugar levels, and continue monitoring sugar levels. Also carry sugar or a sugary drink in case you feel dizzy, or develop any other sign of low blood sugar.

What do I do if I miss a dose?

You can take the missed dose as soon as you remember. If you remember when it is almost time for your next dose, then skip the missed dose entirely. Do not double your dose to catch up for missed doses.

What will happen if I skip a meal?

It is important to maintain regularity in meals, and exercise. Low blood sugar is rare, but may occur if you are taking other anti-diabetic medication.

Will this medicine make me loose or gain weight?

Weight gain is unlikely with this medicine, however, it does cause weight loss. This is because it improves the actions of insulin, and decreases hunger. Please take note that this drug is not a medicine which treats weight loss, and should only be used if prescribed by your physician. This medicine may, however, cause bloating. It is best taken after meals to avoid this side effect.

Can this medication cause any Vitamin deficiency or anemia?

This medication can result in a vitamin B12 deficiency after being used for a long time, and this can cause anemia. Please discuss with your doctor if you are already anemic, or if you start experiencing symptoms such as paleness, weakness, lethargy, etc.

Is it safe to use in patients with liver disease?

In patients who have fatty liver, and hepatitis C related liver disease, it is safe and is recommended. However, it is discouraged in patients who have liver cirrhosis, due to its association with lactic acidosis.

Disclaimer

Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.

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