Triplixam 5mg/1.25mg/5mg tablet

Introduction

How To Use

• Take this medicine by mouth.
• Take this medicine with or without food.
• Take one dose of this medicine, every day.
• Swallow it as a whole, do not crush or chew the medicine.
• Take it at the same time to help you remember.
• Or use it exactly as instructed by your doctor.

Expert Advice

• Take with or without meals.
• To avoid stomachache, take with meals.
• Take missed dose as soon as you remember and next dose in 24 hours.
• Contact prescriber if there is unrelieved headache, vomiting, weight gain, palpitations, or difficulty in breathing.
• Check blood pressure regularly.

Primary Uses

Indications

This medicine is used to treat hypertension (high blood pressure), myocardial ischemia (decreased blood supply to heart muscle) associated with stable (chest pain triggered by activity), or vasospastic angina (chest pain triggered with vasospasm of coronary artery).

Side Effects

Patients using this medicine may commonly experience headache, edema, fatigue, nausea, dizziness (lightheadedness), flushing (reddening of the skin), rashes, and gingival hyperplasia (overgrowth of gum). Patients may rarely experience alopecia (spot baldness), pruritus (itching), abdominal and back pain, hyperglycemia, increased urination, palpitations, and GI (stomach) upset. 

Contraindications

This medicine is contraindicated in patients having history of cardiogenic shock (inability of heart to pump enough blood), aortic stenosis (narrowing of aortic valve opening), unstable angina (chest pain triggered by minimum or no activity), severe hypotension, unstable heart failure following MI, and hypersensitivity to dihydropyridines.

FAQS

Which medicines should be avoided with Amlodidpine?

As per FDA recommendation, simvastatin dosage should be limited to 20 mg daily while taking amlodipine. Also, all the CYP3A4 enzyme inhibitors like diltiazem, ketoconazole, itraconazole & ritonavir should be avoided while taking amlodipine.

I have been experiencing swelling in hands and foot since I started using the medicine. I amconcerned whether this swelling will persist?

You don’t need to worry about the swelling, as it is one of the very common adverse effects of the drug. This will go off once you withdraw its use. But you still need to consult your physician if the condition is getting worse.

When is it safe to discontinue the medicine?

You are not advised to do so abruptly nor are you supposed to make this decision by yourself. Consult with your physician, who will most probably advise for a gradual withdrawal. This is done to avoid the chest pain and relapse of high blood pressure, which is usually observed in such scenarios.

In what forms is the medicine available?

It is available in tablet, drops and I/V (intravenous) forms.

I am a patient of dialysis and have a history of getting treated for hepatitis C too. So, is the medicine safe for me?

No, the drug is not safe for any kind of kidney or liver disease. Consult your physician for an alternative.

What is the best time to take this medicine?

It doesn’t really matter at what time of the day you take amlodipine, but it is best to take it at the exact time every day, for more even blood levels & more effectiveness of the medicine.

Why taking this medicine at night is useful?

New research shows that administering blood pressure medicines at bedtime effectively helps to reduce your risk of illness or death due to blood vessel & heart disease. Timings are important as BP follows a daily rhythm. It is high during the day & falls at nighttime.

How much does this medicine help reduce blood pressure?

It is seen that titration of amlodipine from 5-10 mg every day in patients not responding to the treatment with 5 mg dose showed significant decrease in BP.

Are there any interactions of drugs with this medication?

Yes, this medication can interact with lithium, other diuretics astemizole, bepridil, sulfopride, metformin, NSAIDs, antipsychotics, immunosuppressants and other diuretics.

What is the recommended dosage in adults?

In adults the recommended dosage is 1 tablet in the morning

Can children use this medication?

No, it is not recommended for use in children

Do I have to careful if I have diabetes?

Yes, check blood glucose levels regularly and inform your doctor if there are any changes

When should I contact my doctor?

Contact your doctor if you experience changes in vision, swelling of ankles or hands, respiratory difficulty, unusual bleeding, chest pain, palpitations, numbness, tingling or muscle cramps

Can I stop taking this medicine once my blood pressure is normal?

This medicine should not be stopped unless your doctor recommends it, and it should not be stopped abruptly. Kindly follow the instructions of your physician regarding how and when to stop taking this drug.

Can I stop taking this medicine once my blood pressure is normal?

This medicine should not be stopped unless your doctor recommends it, and it should not be stopped abruptly. Kindly follow the instructions of your physician regarding how and when to stop taking this drug.

Can I get a cough because of this medicine?

Dry cough is a side effect that is associated with this medicine. Please contact your doctor if you cannot tolerate any of the adverse effects after taking this drug.

Can I take painkillers (brufen and asprin) while taking this drug?

Paracetamol can be taken with this medicine. Please consult your doctor if you need to take any other painkiller with this medicine.

Is this medicine a blood thinner?

No, this medicine is not a blood thinner.

Indications:

This medicine is used to treat essential hypertension (high blood pressure) and heart failure.

Administration:

This medicine is mostly taken orally, preferably before meals. The dosage is dependent on the age, condition and its severity. Please consult your doctor before use. This medicine is not recommended for children.

Storage:

Please store this medicine at room temperature. Keep away from excessive light, moisture, and children. Please read the leaflet provided with the medicine for further storage guidance.

Side Effects:

The patients administered with this medicine may experience localized skin rashes, swelling, abdominal pain, fatigue, visual disturbances, paresthesia (sensation of tingling or pricking), mild cough, muscular cramps, flushing, and decrease in hemoglobin levels/platelets.

Precautions:

The patients with renal (kidney) impairment, undergoing surgery or anesthesia, risk of hypotension (low blood pressure), heart abnormalities, undergoing hemodialysis (treatment to filter wastes and excess water from your blood), cholesterol-associated abnormalities, risk of desensitization, and hyperkalemia (high potassium levels) should be cautious. Please monitor serum electrolytes during use of this medicine.

Effects on Pregnancy and Lactation:

This medicine is not recommended during pregnancy. This medicine is not recommended for nursing females.

Contraindications:

The patients with history of swelling associated with such medicines and hereditary or idiopathic swelling (swelling associated with inheritance or unknown causes) should avoid use of this medicine.