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Haemophilia A
Description
Haemophilia is a genetic bleeding disorder in which blood is unable to clot easily due to lack of protein, factor VIII. It is a X linked hereditary disease that is more common in males. People with haemophilia experience excessive internal or external bleeding in response to any injury or trauma which is difficult to stop.
Haemophilia A can be mild, moderate or severe depending upon the availability of factor VIII.
Causes
It is a genetic disorder, either the gene is inherited from the parents or mutation of gene can cause haemophilia
Risk factors
Risk factors of haemophilia include:
- Family history
- Male sex
- Drugs
- Autoimmune disorders etc.
Symptoms
Symptoms of haemophilia depend upon how deficient is factor VIII. Symptoms of haemophilia involves:
- Joint pain,
- Bleeding nose,
- Blood in urine and stools,
- Frequent and excessive bleeding,
- High tendency for bruising etc
Diagnosis
Initially the doctor takes proper history and asks questions regarding the symptoms and asks whether there is family history of haemophilia or not. The definite diagnosis is formulated on the basis of blood tests in which clotting time and deficiency of factor VIII is analysed.
Management
Management of haemophilia A depends upon many factors i.e. age, severity of symptoms and whether blood clots or not. It’s management includes the following:
- Desmopressin
- Infusion of clotting factors
- Antifibrinolytic drugs, they slow the breakdown of clotting factors,
- Handle injuries with extreme caution
- Take safety measures in order to prevent minor injuries etc
When to consult a doctor?
Consult your doctor immediately in case of excessive bleeding due to injury, repetitive vomiting, headache, neck pain, blurred vision etc.
Available Medicine for Haemophilia A
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