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clomiphene

Female infertility due to oligomenorrhoea (mentrual cycle greater than 35 days) or secondary amenorrhoea (absence of mentrual cycles) associated with polycystic ovarian disease. Male infertility. 

Contradications

This medication is contraindicated in patients with liver dysfunction, large ovarian cyst, endometrial carcinoma (cancer in the lining of endometrium), uterine bleeding  (bleeding from uterus), uncontrolled thyroid dysfunction.

Side effects

Ovarian hyperstimulation, hot flushes, abdominal discomfort, visual discomfort, insomnia (inability to sleep), breast tenderness, headache, intermenstrual spotting, menorrhagia (heavy menstrual cylces), weight gain, rashes, dizziness, hairloss, ovarian enlargement, GI upset, urticaria (pale red bumps on skin), alopecia (hairfall in patches), fatigue, jaundice, abnormal LFTs and anxiety.

Expert Advice

Indications:
Female infertility due to oligomenorrhoea (mentrual cycle greater than 35 days) or secondary amenorrhoea (absence of mentrual cycles) associated with polycystic ovarian disease. Male infertility. 

Pregnancy:
This medication is contrainidicated in pregnancy. Comsult your doctor before use.

Lactation:
This medication is contraindicated or not recommeneded in lactating females. Consult your doctor before. 

Precautions:
Multiple pregnancies, patients sensitive to pituitary gonadotrophins eg polycystic ovary disease, blurring or other visual symptoms can occur, ovarian hyperstimulation syndrome (exaggerated response from excess hormones) and abdominal pain. Uterine fibroids (non-cancerous growth of the uterus, depression, risk factors for thrombophlebitis (blood clots in your legs).

Contraindications:
This medication is contraindicated in patients with liver dysfunction, large ovarian cyst, endometrial carcinoma (cancer in the lining of endometrium), uterine bleeding  (bleeding from uterus), uncontrolled thyroid dysfunction.

Side effects:
Ovarian hyperstimulation, hot flushes, abdominal discomfort, visual discomfort, insomnia (inability to sleep), breast tenderness, headache, intermenstrual spotting, menorrhagia (heavy menstrual cylces), weight gain, rashes, dizziness, hairloss, ovarian enlargement, GI upset, urticaria (pale red bumps on skin), alopecia (hairfall in patches), fatigue, jaundice, abnormal LFTs and anxiety.

FAQs

Indications:

This medicine is used for treating infertility in women due to oligo-menorrhea (irregular and menstrual blood flow) or secondary amenorrhea (e.g. absence of menstruation due to conditions such as polycystic ovarian disease). It is also used to treat male infertility.

Storage:

Please store this medicine at room temperature (18-25 Celsius). Keep away from excessive light, moisture, and children. Please read the leaflet provided with the medicine for further storage guidance.

Will I see instant results?

It may take some time for the medicine to work effectively. Use it regularly and as prescribed by your healthcare provider for the best results.

Will taking this medicine affect my skin?

Clomiphene has no significant effects on the skin.

Precautions:

The patients with sensitivity to gonadotrophins (e.g. polycystic ovary disease), multiple pregnancies, visual disturbances, ovarian hyper-stimulation syndrome (exaggerated response due to hormone excess), abdominal pain, uterine fibroids (noncancerous uterine growths), depression, and risk of thrombophlebitis (inflammation causing blood clot formation in veins).

Effects on pregnancy and lactation:

This medicine is not recommended for pregnant females. This medicine is not recommended for nursing females.

Side Effects:

The patients administered with this medicine may experience ovarian hyper-stimulation (exaggerated response due to hormone excess) and visual blurring after withdrawal, hot flushes, insomnia, breast tenderness, intermenstrual spotting, menorrhagia (abnormally heavy or prolonged menstruation), endometriosis (growth of uterine tissue outside uterus), convulsions, weight gain, hair loss, ovarian enlargement, gastrointestinal disturbances, urticaria (round, itchy welts), alopecia (abnormal hair loss), abnormal liver function tests, anxiety and jaundice.

Administration:

This medicine is mostly taken orally. The dosage is dependent on the age, and condition and its severity. Please consult your doctor before use. This medicine is not recommended for children.

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