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ivabradine

This medcine is indicated in chronic stable angina (consistent duration and severity of brief episodes of pain, pressure, squeezing and tightness in chest), coronary artery disease (narrowing or blockage of arteries of heart muscles) with normal sinus rhythm (normal heart rate) who have a contraindication or intolerance to beta blockers when monotherapy is inadequate and heart rate is more than 60 beats per minute.  It is also used in patients with stable chronic heart failure, with systolic dysfunction (impairment in contraction of ventricles). In patients with stable chronic heart failure (chronic heart failure in which clinical condition didn’t get any worse) with systolic dysfunction (impairment in contraction of ventricles), in sinus rhythm (pace with which heart beats) rate equals to 75 beats per minute in combination with standard therapy, including beta blockers or when beta blockers are contraindicated, or not tolerated. 

Contradications

It is contraindicated in patients with pretreatment heart rate less than 60 beats per minute, persistent symptoms of bradycardia (very low heart rate) or if heart rate is persistently below 50 beats per minute, cardiogenic shock (a condition in which heart suddenly fails to pump enough blood to meet your  body’s requirement), acute myocardial infarction (heart attack), severe hypotension (low blood pressure) (less than 90/50 mm Hg), sick sinus syndrome (a condition in which heart’s natural pacemaker is unable to create appropriate heart rate), sino atrial block (disorder in normal rhythm of heart, that started at SA node), unstable or acute heart failure (heart failure in which clinical condition is worsening), pacemaker dependent, unstable angina (condition in which heart is deprived of sufficient blood flow and oxygen), 2nd (conduction of atrial impulse through AV node is blocked or delayed) or 3rd (abnormal heart rhythm due to defect in conduction system) degree AV block, cardiac arrhythmias (abnormal heart rhythms), severe hepatic (liver) impairment or in patients immediately after stroke.

Side effects

Its side effects include blurred vision, bradycardia (slow heart rate), 1st degree AV block (when there is a delay in conduction), ventricular extrasystole (premature contraction of ventricles), blood pressure changes, dizziness, headache etc.

Expert Advice

  • Take with meals.

  • Avoid excessive intake of grapefruit juice.

  • Inform prescriber before starting the medication if any surgery is due.

FAQs

When should I take Ivabradine?

Take two doses, one with breakfast and the second dose with the evening meal.

What are the side effects of Ivabradine?

Blurred vision, irregular heart beat, chest discomfort, dizziness, tiredness etc are some of its side effects.

What is the purpose of Ivabradine?

It is used to treat adults with heart failure (inability of heart to pump sufficient blood) to lower the risk that the condition will get worse.

Does Ivabradine make you tired?

Dizziness and tiredness may occur.

Can Ivabradine cause breathlessness?

Yes, It may cause breathlessness.

Medicines containing ivabradine

Ivatab 5mg

By Nabi Qasim

Pack size: 2x7's

Rs.324.5

Coralan 5mg

By Servier

Pack size: 56

Rs.490

Coralan 7.5mg

By Servier

Pack size: 1400

Rs.1960

Ivagen 5mg

By Genix

Pack size: 1x14's

Rs.420

Ivagen 7.5mg

By Genix

Pack size: 1x14's

Rs.420

Ivaset 5mg

By Highnoon

Pack size: 2 x 7's

Rs.182

Ivaset 7.5mg

By Highnoon

Pack size: 1x14's

Rs.280

Ivatab 5mg

By Nabi Qasim

Pack size: 2x14's

Rs.462

Ivatab 7.5mg

By Nabi Qasim

Pack size: 2x7's

Rs.217

Sivab 5 mg

By Getz Pharma

Pack size: 2 x 7's

Rs.267

Sivab 7.5 mg

By Getz Pharma

Pack size: 1 x 14's

Rs.410

Sivab 7.5 mg

By Getz Pharma

Pack size: 2 x 7's

Rs.222.5