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Glucobay 100mg tablet

Manufacturer : Bayer

Rs. 114.50

Rs 134.71
Per Strip

Rs.13.47/tablet

10 tablet(s) in 1 Strip

Pack Size : 3 x 10s

Rs.404.13/Pack


Prescription Required

Glucobay 100mg tablet is composed of

Acarbose (100mg)
Dawaai Fast

Primarily used for


Type 2 diabetes

Belongs to the category

Hypoglycemics

Precaution:

As a precaution please monitor hepatic transaminase (liver enzyme).

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Acarbose C25H43NO18
Molecular Weight: 645.608 g/mol
Dissociation Constant: 5.1

Indication

It is primarily indicated for treating Diabetes Mellitus type 2, used in combination with other line agents.

Mechanism of Action

Acarbose is known to be pseudotetrasacchride that inhibits absorption of glucose by delayed ingestion by inhibiting the pancreatic aplha amylase enzyme and alpha glucosidase enzyme present in the brush border of the intestine which prevents the breakdown of complex carbohydrates into monosacchride and starch

Dosage

Strength: 100mg

Form: tablet

Dosing interval: 8 Hr

Maximum Dose: Research suggests that the maximum dose given to an individual of 60kg or less should be 50 mg (8-hourly) and above 60kg should be 100mg (8-hourly)

Dialyzable:Data not available, so not recommended or monitor with care.

Maintainance dose

It is suggested to start the dose with 25mg three times a day and can be increased upto 50-100mg three times a day depending upon tolerance and glucose levels (HbA1C, random and fasting blood glucose test)

Hepatic Adjustment

It is suggested to obtain transaminase level before initiation in liver insufficiency to prevent worsened conditions.

Renal Adjustment

It is advised to take cautiously when serum creatinine levels are less than 2mg/dl

  • Pregnancy

    Can be used but doctor consultation is important before use, as human and animal research is insufficient or animals showed defects and human research hasn?t been conducted.

  • Lactation

    Insufficient data to prove if the drug enters breast milk, hence not recommended.

ContraIndication
Cautions

Evidences of severe hypoglycemia reported when using along with insulins and sulfonylureas. Incidents like; Trauma,surgery, stress and fever have proven to cause loss over glucose regulation

Pharmacokinetics

Time of onset: 1 Hr

Tmax: 0.32 Litres per kg

Bioavailability: less than 2%

Protein Binding : It is known to be greater than 99% as per reported data.

Elimination Half Life (t1/2): 2 Hr

Metabolism: By digestive system as per researches.

Volume of Distribution (Vd): 0.32 Litres per kg

Metabolites:

4-Methylpyrgallol derivatives as inactive metabolite

Medicine Overview of Glucobay 100mg tablet

Uses of Glucobay

This medicine is used for managing non-insulin dependent diabetes

Side effects of Glucobay

Some patients might experience stomach bloating, stomach pain and diarrhoea. Please consult your doctor if you experience any of these symptoms.

When not to use Glucobay

Please consult your doctor before taking this medicine if you have any of these conditions; Hepatic or renal impairment (liver or kidney disorder) or any of the following stomach disorders like inflammatory bowel disorders, chronic ulcerations, intestinal obstructions, or chronic digestive or absorption problems.

How to take Glucobay

This medicine should be taken with food.

Warnings

  • Driving

    Please avoid driving when taking this medicine as it may affect your ability to drive.

  • Pregnancy

    Please consult your doctor before taking this medicne.

  • Breast Feeding

    Research suggests that this medicine should be avoided by women who are breastfeeding.

What side-effects did you experience while using this medicine?

  • stomach pain 1
  • skin rash 0
  • flatulence 0
  • diarrhea 0
  • None 0

How did you take this medicine?

With food


100%

With or without food


0%

Empty Stomach


0%

How much was the improvement?

1


0%

2


0%

3


0%

4


100%

5


0%

What are you using this medicine for?

Type 2 diabetes


0%

Others


0%

Number of survey's Available: 1

Question 1

What are you using this medicine for?

Question 2

How much was the improvement?

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How did you take this medicine?

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What side-effects did you experience while using this medicine?

Question 5

Any precautions you had to take while using this medicine?