OVERVIEW:
What is the 17-OH progesterone lab test?
17-OH progesterone serum lab test is a blood test that measures the level of 17-hydroxyprogesterone in the blood.
Why is the 17-OH progesterone lab test done?
17-OH progesterone lab test is done in order to:
- Diagnose congenital (since birth) adrenal hyperplasia (enlargement of adrenal gland).
- Check the level of 17-hydroxyprogesterone in newborn babies.
What does a 17-OH progesterone lab test measure?
A 17-OH progesterone lab test measures the level of 17-hydroxyprogesterone circulating in the blood. 17-hydroxyprogesterone is a hormone that is produced by the adrenal glands. An excess of 17-OH progesterone in the blood is indicative of congenital (since birth) adrenal hyperplasia (enlargement of adrenal gland).
Are there any risks associated with this test?
This test may cause a slight bruise or soreness around the area where the needle was inserted.
How should I prepare for this test?
Your doctor may advise you to stop eating or drinking 8 hours before the test. Fasting is not necessary for infants. Your doctor may also ask you to stop taking medicines that might interfere with the test results.
When do you check 17 OH progesterone?
Your baby will need a 17-OHP test, usually within 1–2 days after birth.
What does a high 17 hydroxyprogesterone mean?
High levels of 17-OH progesterone can indicate a condition called congenital (since birth) adrenal hyperplasia (enlargement of adrenal gland).
How long will this test take?
This test may take around 30 minutes.
INTERPRETATION OF THE RESULT:
A high level of 17-OH progesterone may be due to:
- Tumors of the adrenal gland
- Congenital adrenal hyperplasia
Normal 17-OH progesterone results mean that it is likely that the person tested does not have congenital adrenal hyperplasia
Low or decreasing concentrations in a person with CAH indicate a response to the treatment
