What is this test?
- This laboratory test is performed on a blood sample to detect the presence of atypical alloantibodies against a red cell antigen. Alloantibodies are the antibodies produced against foreign (non-self) antigens.
Why is this test performed?
- To detect antibodies in patients requiring blood transfusions
- To detect antibodies in pregnant females
- To detect antibodies in patients with suspected transfusion reactions
- To detect the presence of antibodies in blood donors
- To investigate immune-mediated hemolytic anemia
- To determine the risk of Hemolytic disease of newborn.
- What are alloantibodies?
Alloantibodies are the antibodies produced against foreign (non-self) antigen. Alloantibodies are made in response to transfusion of red cells or exposure to red cells from the fetus.
- Do I need to fast before this test?
No, fasting is not required before this test.
- How to prepare for this test?
No special preparations are required for this test. Inform your doctor about the use of all prescribed and non-prescribed medicines. Wear a short-sleeved shirt to aid the collection of sample.
- What are the risks of this test?
Collecting blood from a vein is a very easy procedure and pose only minimum risk, including:
- Bruising
- Bleeding
- Infection
- What is the use of pre-transfusion testing?
Pre-transfusion testing is done to check if the red blood cells will survive when transfused to the patient. It checks ABO compatibility and RBC alloantibodies that can react with blood from the donor.