: Usually, the immune system can discriminate between foreign substances ("non-self") and the bodys own cells ("self"). It produces antibodies only when it perceives that it has been exposed to a threat ("non-self"), such asbacteria or viruses. However, when the immune system ceases to recognize one or more of the body's normal constituents as "self," it may produce autoantibodies that react with its own cells, tissues, and/or organs. This may causeinflammation, damage, and dysfunction of organs or systems, leading to signs and symptoms ofautoimmune disorders.
ANTIPHOSPHOLIPID SYNDROME (APS)
Most abundant, gives protection against bacterial and viral infections.
WHAT DOES THE TEST MEASURE?
A positive beta- 2 glycoprotein IgG antibody test indicates that the person has Antiphospholipid syndrome, as they are most frequently see with the condition.
A negative beta- 2 glycoprotein IgG antibody but positive for other antiphospholipid antibodies and has signs and symptoms, then the person has APS.
A single positive beta-2 glycoprotein 1 antibody result is not diagnostic of APS, and a negative result does not rule out antiphospholipid antibody development. They just indicate the presence or absence of the antibody at the time of testing. That is why a diagnosis of APS requires clinical symptoms plus at least two positive tests for an antiphospholipid antibody at least 12 weeks apart.
1. How is the test performed?
This test is performed on a blood sample by inserting a needle into a vein.
2. Is any test preparation needed?
No test preparation needed
3. Can antibodies go away?
Antibodies will be found in the blood of patients who were ever positive.
WHY IS THIS TEST PERFORMED?
To help investigate inappropriate blood clot formation
To help investigate the cause of recurrent miscarriages
As part of an evaluation for antiphospholipid syndrome