What is this test?
This laboratory test is performed on a Cerebrospinal fluid sample to detect the presence of Mycobacterium tuberculosis (Acid-fast bacilli) on the culture and guide antimicrobial therapy. It helps in the diagnosis of tuberculous meningitis.
Why is this test performed?
This test is performed to detect tuberculous meningitis caused by Mycobacterium tuberculosis. The bacteria sometimes travel to the meninges (membranes surrounding brain and spine) and causes inflammation called tuberculous meningitis.
- What are the complications of tuberculous meningitis?
- Brain damage
- Seizures
- Hearing loss
- Stroke
- Increased pressure in brain.
- Which medicines are used to treat tuberculous meningitis?
- Isoniazid
- Rifampicin
- Pyrazinamide
- Moxifloxacin
- What are the risks of this test?
- Bleeding
- Infection
- Damage to spinal cord nerves
- Headache after the test
- CSF leakage from injection site
- Allergic reaction to anesthetic.
- How to prepare for this test?
Empty your bladder and bowel before the test. Inform your doctor about your completed medical history, especially of medicine such as blood-thinners and allergies.
- What is cerebrospinal fluid?
Cerebrospinal fluid is a colorless liquid the bathes the brain and spinal cord. It plays a very important role in cushioning the central nervous system. It also provides nutrients to the spine and eliminates waste products.
- Is the procedure painful?
No, a numbing medicine is used to make it a painless procedure. However, pressure is felt from the needle.
- Interpretation of test results:
Positive: Pathogenic organism (Mycobacterium tuberculosis) detected and identified on culture. The bacteria is further tested for sensitivity and the appropriate antibiotic is mentioned in the reports.
Negative: No growth on culture is seen. Mycobacterium tuberculosis is absent.
