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Expert Advice


  • Take with or without meals.
  • Take a single daily dose in the morning.
  • Do not stop taking medication abruptly.
  • Avoid alcohol or caffeine during therapy.
  • Take sufficient amounts of fluids (2-3 liters per day) to maintain hydration unless restricted by the prescriber,
  • Maintain regular dietary intake to avoid excessive weight loss
  • Change position slowly from sitting or lying to standing.
  • If you have diabetes, check your blood glucose regularly and inform the prescriber about the changes.
  • On start of therapy and change of dosage, the patient should be watched carefully for suicidal tendencies by family.











Primary Uses


This medicine is used to treat depression, especially in cases where sedation is not required; as well as for the treatment of bulimia nervosa (an eating disorder characterised by binge eating and followed by voluntarily vomiting) and obsessive-compulsive disorder (a mental disorder in which people have unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), and behaviors that drive them to do something repititively). 

Side Effects

The adverse effects of this medicine are nausea, headache, anxiety, vomiting, insomnia (lack of sleep), dizziness, asthenia (weakness in muscles), rash, convulsions (a sudden, violent, irregular movement of the body, caused by involuntary contraction of muscles and associated especially with brain disorders) , hypomania and mania (mental illness marked by periods of great excitement, delusions, and overactivity) , anorexia, sleep disorders, restlessness, decreased libido (decreased desire for sexual function), disturbance in attention, dysgeusia (distortion of taste), somnolence (increased sleep), tremor, blurred vision, palpitations (sensation of heart pounding), QT prolongation (disorder in ECG), flushing, yawning, GI upset, dry mouth, rash, and allergic reaction, increased sweating,  arthralgia (pain in joint), urinary frequency, gynaecological bleeding, sexual dysfunction, fatigue, chills, weight loss, serotonin syndrome (a condition in which symptoms include high body temperature, agitation, increased reflexes, tremor, sweating, dilated pupils, and diarrhea), bleeding disorders, seizures, erythma multiform (it is a hypersensitvity reaction which may occur due to herpes simplex virus). In Children and adolescents: suicide-related behavior, mania, hypomania, epistaxis (bleeding of the nose), growth retardation, decreased alkaline phosphatase can be seen with the use of this medicine.   



The risk of this medication is undetermined in pregnant females; therefore, caution is advised. Consult your doctor before the use of this medicine.


This medicine is contraindicated to use in lactation. Please consult your doctor for further assistance. 


Use this medicine cautiously in liver impairment, diabetes, heart disease, stable epilepsy (a condition in which patient may have sudden seizures), psychosis, ECT ( an electric shock therapy given to trigger epileptic seizure), mania   (a mental illness marked by periods of great excitement, delusions, and overactivity), if there is a risk of bleeding, raised IOP (intraocular pressure), narrow-angle glaucoma ( a condition in the eye which causes increased pressure in the eye), or a history of glaucoma. Monitor for suicidal ideation in patients using this medicine. The use of this drug may cause risk factors for QT prolongation (a disorder in ECG) or torsades de pointes (a condition in which there is an irregular ECG). Advice patients to report if they experience any heart symptoms. Monitor growth and pubertal development in children during and after treatment. A dose increase of this medicine may be detrimental in patients who develop akathisia (a movement disorder characterized by a feeling of inner restlessness and inability to stay still). This drug is poor CYP2C19 metabolizers. Use this drug cautiously in elderly patients and withdraw gradually if adverse symptoms appear.


This medicine is contraindicated in severe renal (kidney) failure, unstable epilepsy (a disorder with abnormal brain activity causing seizures). It is also not prescribed within 2 weeks of stopping MAOIs and 1 day of stopping moclobemide.


Is this medicine a safe antidepressant?

Yes, this medicine is considered safe and effective.

What does this medicine do to your body?

This medicine works by increasing the amount of Serotonin in your brain.

Can this medicine cause weight gain?

Yes, antidepressants usually cause weight gain.

How long can I take this medicine?

Most patients take this medicine for 6 months to 12 months. Follow your prescribers advice,

What will happen if I stop taking this medicine?

Missing doses of this medicine may increase your risk of relapse of symptoms


Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.


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