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This medicine is used for oedema (swelling) associated with congestive heart failure (heart disorder), hepatic ascites (fluid in abdomen due to liver disorder) and kidney disease where potasssium supplement is required.
Patients taking this medicine may experience gynaecomastia(hormone imbalance), GI upset (upset stomach), rash, drowsiness, headache, or confusion. Please consult your doctor if you experience any of these symptoms.
Please consult your doctor before taking this medicine if you have anuria (kidneys unable to produce urine), renal failure (kidney disorder) or hyperkalaemia(high level of potassium).
This medicine should be taken with food.
Hypertension

This medication is used for lowering blood pressure in hypertensive (increased blood pressure) patients and for treating edema (excess fluid in the body) associated with heart disease. It can also be used to treat Nephrotic Syndrome.

Patients administered with this medicine may experience anorexia (eating disorder characterized by abnormally low body weight) and epigastric distress (pain right below ribs, in the upper abdomen (stomach area).

This medicine is contraindicated in patients suffering from renal (kidney) decompensation and anuria (non-passage of urine).

  • Take with meals.
  • Change position slowly.
  • Include potassium rich foods in diet such as bananas and orange juice.
  • If you have diabetes, check blood sugar level regularly and inform prescriber about changes.
Hypertension
It is a potassium sparing diuretic, which means it blocks a certain hormone’s action which allows for more fluid and less potassium to pass through the kidney.
Captopril is an ACE inhibitor and research suggests that it interacts with spironolactone. It is recommended that you refrain from the use of these two drugs together because it can cause hyperkalemia (increased potassium levels in blood).
Yes, has been used at lower doses to treat acne in females by combining it with an oral contraceptive. However, it is not a quick fix and isn’t recommended as a treatment yet and should only be taken if advised by your doctor.
It is not recommended to be used in males because it makes the skin less responsive to androgens and feminizes a man. A common side effect of this drug in males is gynaecomastia (enlargement of breasts).
Yes, irregular periods are a common side effect of this drug. Please consult your doctor if you are experiencing this side effect.
There is no harm in crushing the tablet for swallowing if required, however it is best to take it whole with water.
Yes, it has been used as a treatment for hirsutism because it decreases testosterone levels. Please do not use this drug to treat hirustism unless advised otherwise by your doctor.
When indomethacin is used, it increases the diuretic effect of spironolactone and together they may cause an increase in the potassium levels in the blood. Let your doctor know if you are on indomethacin before starting treatment with this drug.
It does not reduce the efficacy of your birth control/OCP. When taken with it, it helps in reducing hormonal acne and hirsutism in women.
Yes, it has been reported to cause hyponatremia (very low amounts of sodium in blood). Please consult your doctor if you are suffering from the signs and symptoms of hyponatremia which are lethargy, restlessness, muscle weakness, confusion, irritability, drowsiness or fatigue.
Yes, it is both a potassium sparing diuretic which helps in the excretion of excess fluids from the body and a synthetic steroid which works by blocking the effect of mainly the hormone aldosterone; and testosterone as well.
Spironolactone raises the risk of breast cancer in women. Talk to your doctor if you have a family history of cancer or have any concerns related to this side effect.
It has not been reported to cause any increase or decrease in the estrogen levels. Being a synthetic steroid, it blocks the effects of aldosterone and testosterone; in turn producing effects that are very similar to those of the hormone progesterone.
The more common side effects that can occur with hydrochlorothiazide include blood pressure that is lower than normal (especially when standing up after sitting or lying down), dizziness (feeling like sleeping), headache, and weakness.
If you are to take a single dose a day, take it in the morning after breakfast. If you are to take more than one dose a day, take the last dose no later than 6 p.m., unless otherwise directed by your doctor.
Hydrochlorothiazide belongs to a class of medicine known as diuretics water pills. It works by causing you to make more urine. This helps your body get rid of extra salt and water. This medicine also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease.
This medicine is mostly used orally. The dose is dependent on the age, condition and its severity.
Drinking alcohol with this medicine can cause side effects.
Please store this medicine at room temperature away from excessive light, moisture, and children.
Pharmacological effects begin in about 2 hours after an oral dose, peaks in 4 hours, and lasts for about 6 to 12 hours.
Please consult your doctor before taking this medicine
Research suggests that women who are breastfeeding should avoid taking this medicine.
Please avoid driving when taking this medicine as it may affect your ability to drive.
Patients with kidney and liver impairment should consult their doctor before taking this medicine.
This medicine is contraindicated in pregnant females.
This medicine is contraindicated in lactating females. 
Please avoid driving when taking this medicine as it may affect your ability to drive.
Please avoid consuming alcohol when taking this medicine.
Avoid this medicine in severe renal (kidney) disease. Patients suffering from gout (painful joints), diabetes (raised blood sugar level), and moderate to high cholesterol concentration should stay cautious.

Disclaimer

Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.

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