Amaryl-M 2mg/500mg sr tablet

Name: Amaryl-M
Brand: Sanofi
SKU: SANAMA11273
Price: 224 PKR
Availability: InStock

Brand: Sanofi

Prescription Required

Hypoglycaemic excluding Insulin

Amaryl-M 2mg/500mg sr tablet is composed of Glimepiride (2mg)Metformin (500mg)

Overview
FAQS
Warnings

Uses

This medication is used for managing non-insulin dependent diabetes

Side Effects

Some patients might experience hypoglycemia and liver failure. Please consult your doctor if you experience any of these symptoms.

When Not To Use

Please consult your doctor before taking this medication if you have any of these conditions; insulin-dependent diabetes mellitus (type of diabetes), or diabetic Ketoacidosis (diabetic complication).

How To Use

This medicine should be taken with food.

Expert Advice

Avoid this medication if:

You are allergic to this medicine or it's contents (Sulfa, etc.)

Consult your doctor if:

You are pregnant, planning to have a child, or breastfeeding.
You have any sort of digestive problems.
You have a medical history of: Liver diseases, kidney diseases, thyroid problems, blood disorders, etc.
Inform your physician about any other medication you are taking. Especially NSAIDs, thyroid medicines or blood pressure medications (such as Beta Blockers, or ACE inhibitors.)

Be careful about:

Having your meals on time to maintain blood sugar levels

Taking the medicine timely, in the way that your physician has prescribed (with food)

Following the lifestyle changes that your physician has suggested.
Alcohol consumption should be avoided.

Effective

Type II Diabetes

Uses

This medicine is indicated in maturity onset diabetes either alone or with sulphonylureas. It is also used as adjuvant therapy in insulin dependent diabetes, particularly in obese patients.

Side Effects

GI upset, taste disturbance, abnormal liver function tests, hepatitis (inflammatory condition of liver), skin reactions, reduced B12 absorption are some of its side effects. Rarely it may cause lactic acidosis (buildup of lactate causing acidic pH of blood stream).

When Not To Use

This medicine is contraindicated in patients with diabetic ketoacidosis (life threatening condition in which liver breaks down fats into ketones for energy) or precoma (a state of near unconsciousness), renal (kidney) or hepatic (liver) impairment, acute conditions predisposing to renal impairment, cardiac or respiratory failure, recent myocardial infarction (heart attack), alcoholism and in patients with administration of iodinated contrast materials.

How To Use

This medicine should be taken with food.

Expert Advice

Avoid this medication if:

You are allergic to this medicine or its contents

Consult your doctor if:

You are pregnant, planning to have a child, or breastfeeding.
If you are avoiding unwanted pregnancy, so that your doctor may suggest a suitable form of birth control. Due to Metformin's effects on ovulation and pregnancy.
You have any sort of digestive problems after taking this medicine: Nausea, vomiting, diarrhea, etc.
You have a medical history of: Liver diseases, kidney diseases, congestive heart failure, or lung disease.
If you are about to undergo any medical or surgical treatment.
If you are about to undergo any CT scan, or X-ray, as it may interact with the dyes used in some pf these procedures.
If you have a B12 deficiency, are anemic, or are developing symptoms of anemia, Such as: lethargy, aches and pains, or a pale appearance to the skin.

Be careful about:

Having your meals on time to maintain blood sugar levels.
Taking the medicine timely, in the way that your physician has prescribed (with food), this will help avoid digestive disturbances.
Alcohol consumption.
Avoiding dehydration in any form.

Effective

Type II diabetes

What family of drugs does this medicine belong to?

This drug belongs to a class of drugs known as sulfonylureas. These drugs are used in the treatment and management of diabetes.

Is it safe to have Glimepiride with other anti-diabetic medications such as Sitagliptin?

It is safe to take these medications together, if your physician has recommended it. However, it is important to be even more careful about your meals and dosing schedule, to lower the risk of low blood sugar.

Can this drug be used with Insulin?

If your physician has recommended adding insulin to your treatment, then it should be taken along with this drug. Please make sure that you do not change the prescribed doses in any way, since this may cause changes in blood sugar levels.

Is it better to take metformin with this drug?

Metformin belongs to a different class of drugs, and it can be used along with this drug to improve blood sugar levels. It is safe to take metformin along with this drug, only if your doctor recommends it, and keeping the necessary precautions in mind.

Can this medicine cause low blood sugar?

This is a possible side effect, but can be avoided if meals are taken regularly.

Is this drug safe to use during pregnancy?

No. This drug is not recommended for use in pregnancy. Please consult your doctor before using it during pregnancy.

Can I use this drug during lactation?

No. The use of this medication is not recommended for use during lactation. Please consult your doctor before using this drug during breast feeding.

Can I use this medicine if I have a kidney disease?

This medicine is not recommended for use in kidney problems because it can further worsen the condition. Please consult your doctor for further assistance.

Can I use this medication if I have a liver impairment?

Glimepiride is advised to use cautiously in patients with liver disease. Your doctor may carefully alter the doses if you suffer from it.

What will happen if I skip glimepiride for few days?

This medicine should not be skipped as it can worsen your diabetes. If however, this medication is missed, take the missed pill as soon as you remember but do not double the dose. Complete the full course as recommended by your doctor.

Can I use this drug if I have sulfa allergy?

Avoid using this drug if you are allergic to sulfonylureas or sulfonamides.

Can I use this drug with my blood pressure medicine?

Certain blood pressure medicines may increase the effect of glimepiride and cause the blood sugar levels to fall even more causing hypoglycemia. For this reason, you must consult your doctor before starting therapy with this drug along with any hypertension medicines.

What family of drugs does this medicine belong to?

Metformin belongs to a class of drugs known as biguanides. It is used to improve insulin activity, and control weight in diabetic patients. It is also known to regulate menstrual cycles (periods) and is used in the treatment of PCOs (Poly Cystic Ovarian Disease.)

Does this medicine contain hormones, or insulin?

No, this drug does not contain hormones, or insulin,. It enhances the effect of insulin, which helps patients with diabetes or PCOs, since their bodies tend to develop a resistance to the actions of insulin.

Can this drug be used with thyroid medications, and steroids?

Though there is no dangerous drug interaction, an adjustment in doses of both anti thyroid drugs, and steroids (eg: prednisone) may be required. It should be noted that patients taking steroids sometimes develop diabetes as a side effect. Please consult your physician, and discuss all the medicines you are taking, including their doses.

What is lactic acidosis and does this medication cause it?

Lactic acidosis is a very rare, and potentially fatal side effect of this medication. It occurs when there is an excessive buildup of lactic acid in the body. It may occur in patients who have overdosed. Symptoms include stomach problems, dizziness, breathing difficulty, muscle aches, irregular heartbeat, etc. Patients who experience these symptoms should go to a doctor immediately.

How long should I use this medication for?

Please use this medicine for the time that has been prescribed, and in the dose prescribed by your physician. Using it for longer than prescribed can cause side effects such as Vitamin B12 deficiency.

Can this medicine cause low blood sugar?

Low blood sugar is rare with Metformin, but it is a possible side effect, especially if you are taking other anti-diabetic drugs. Please maintain regularity in meals, dosage, and exercise to maintain blood sugar levels, and continue monitoring sugar levels. Also carry sugar or a sugary drink in case you feel dizzy, or develop any other sign of low blood sugar.

What do I do if I miss a dose?

You can take the missed dose as soon as you remember. If you remember when it is almost time for your next dose, then skip the missed dose entirely. Do not double your dose to catch up for missed doses.

What will happen if I skip a meal?

It is important to maintain regularity in meals, and exercise. Low blood sugar is rare, but may occur if you are taking other anti-diabetic medication.

Will this medicine make me loose or gain weight?

Weight gain is unlikely with this medicine, however, it does cause weight loss. This is because it improves the actions of insulin, and decreases hunger. Please take note that this drug is not a medicine which treats weight loss, and should only be used if prescribed by your physician. This medicine may, however, cause bloating. It is best taken after meals to avoid this side effect.

Can this medication cause any Vitamin deficiency or anemia?

This medication can result in a vitamin B12 deficiency after being used for a long time, and this can cause anemia. Please discuss with your doctor if you are already anemic, or if you start experiencing symptoms such as paleness, weakness, lethargy, etc.

Is it safe to use in patients with liver disease?

In patients who have fatty liver, and hepatitis C related liver disease, it is safe and is recommended. However, it is discouraged in patients who have liver cirrhosis, due to its association with lactic acidosis.

Pregnancy

Research suggests that this medication should be avoided by pregnant women.

Lactation

Research suggests this medication should be avoided by women who are breastfeeding.

Driving

Please avoid driving when taking this medicine as it may affect your ability to drive.

Alcohol

Please avoid consuming alcohol when taking this medicine.

Precautions

Please regularly monitor blood glucose levels.

Pregnancy

This medicine is safe to use in pregnant females. No evidence of risk found.

Lactation

This medicine is contraindicated in lactating females.

Alcohol

Please avoid consuming alcohol when taking this medicine.

Precautions

Assess risk factors for lactic acidosis (buildup of lactate causing acidic pH of blood stream). Discontinue immediately if metabolic acidosis (overproduction of acid in the body) is suspected. Monitor renal (kidney) function at least annually. Discontinue the medicine for 48 hours before and after the elective surgery.

Related Lab Tests

Blood Glucose Fasting Lab Test
Insulin (Fasting) Lab Test
HbA1C (Glycosylated Hemoglobin) Lab Test

Disclaimer

Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.

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