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Primarily used for
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Precaution:
Please consult your doctor as a precaution before taking this medicine if you have cross-sensivity to sulfonamides and sulfonamide derivative (type of antibiotic).
It is primarily indicated for treating Diabetes Mellitus type 2. Orphan (rare medication use): Acute spinal cord injury, stroke and hemorrhage
It increases B cell insulin secretion, receptors and sensitivity. It also decreases the liver production of glucose
Strength: 5mg
Form: tablet
Dosing interval: Every 24 hours usually. Administer every 12 hourly for doses less than 10mg
Maximum Dose: 20mg per day
Dialyzable:The medicine is not dialyzable. Hence, suggested to avoid in renal insufficient patients.
Studies suggests to start with a dose of 2.5-5mg per day then adjust up to 7.5-12mg per day.
It has been suggested to start with 1.25mg of Glibenclamide initially in patients who have a compromised liver functioning as per studies.
It is not suggested in patients with Creatinine Clearence less than 50ml/min: Suggested to be used with caution.
Doctors consultation is important before use, as human and animal research is insufficient or animals showed defects and human research hasn?t been conducted.
Insufficient data to prove if the drug enters breast milk, hence not recommended.
Should be taken with great care in patients who have renal and kidney dysfunction. Also it is suggested to observe blood levels for anemic conditions that might develop due to 6-phosphate glucose dehydrogenase deficiency conditions. Pregnant and nursing mothers should be closely monitored for altered glucose levels.
Time of onset: 1 Hr
Tmax: 9.5 Liters
Bioavailability: Variable
Protein Binding : 99%
Elimination Half Life (t1/2): 1.4-1.8 Hr for active drug. Ten hours for metabolites.
Metabolism: Less metabolites formed through extensive liver metabolism
Volume of Distribution (Vd): 9.5 Liters
Active: 3-cis-hydroxyglyburide
Uses of EugluconThis medicine is used for managing maturity onset diabetes
Side effects of EugluconSome patients might experience Nausea. Pease consult your doctor if you experience any of these symptoms.
When not to use EugluconPlease consult your doctor before taking this medicine if you have any of these conditions; Juvenile diabetes with Ketosis (type of diabetes), impairment of renal function (kidney disorder), stress, diabetic coma.
How to take EugluconThis medicine should be taken with food.
Expert Advice for Euglucon
Avoid this medication if:
Consult your doctor if:
Be careful about:
Please avoid driving when taking this medicine as it may affect your ability to drive.
Please avoid consuming alcohol when taking this medicine.
Please consult your doctor before taking this medicne.
Research suggests that this medicine should be avoided by women who are breastfeeding.
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