Glucovance 1.25mg/250mg tablet

Name: Glucovance
Brand: Martin Dow Marker
SKU: MERGLU10996
Price: 30 PKR
Availability: InStock

Brand: Martin Dow Marker

Prescription Required

Hypoglycaemic excluding Insulin

Glucovance 1.25mg/250mg tablet is composed of Glibenclamide (1.25mg)Metformin (250mg)

Overview
FAQS
Warnings

Uses

This medicine is used for managing maturity onset diabetes

Side Effects

Some patients might experience Nausea. Pease consult your doctor if you experience any of these symptoms.

When Not To Use

Please consult your doctor before taking this medicine if you have any of these conditions; Juvenile diabetes with Ketosis (type of diabetes), impairment of renal function (kidney disorder), stress, diabetic coma.

How To Use

This medicine should be taken with food.

Expert Advice

Avoid this medication if:

You are allergic to this medicine or it's contents, (Sulfa, etc.)

Consult your doctor if:

You are pregnant, planning to have a child, or breastfeeding.
You have any sort of digestive problems
You have a medical history of: Liver diseases, kidney diseases, thyroid problems, blood disorders, etc.
You are considered an elderly patient, since this medicine may cause low blood sugar in such patients.
Inform your physician about any other medication you are taking.

Be careful about:

Having your meals on time to maintain blood sugar levels
Taking the medicine timely, in the way that your physician has prescribed (with food)
Following the lifestyle changes that your physician has suggested.

Effective

Type II Diabetes

Uses

This medicine is indicated in maturity onset diabetes either alone or with sulphonylureas. It is also used as adjuvant therapy in insulin dependent diabetes, particularly in obese patients.

Side Effects

GI upset, taste disturbance, abnormal liver function tests, hepatitis (inflammatory condition of liver), skin reactions, reduced B12 absorption are some of its side effects. Rarely it may cause lactic acidosis (buildup of lactate causing acidic pH of blood stream).

When Not To Use

This medicine is contraindicated in patients with diabetic ketoacidosis (life threatening condition in which liver breaks down fats into ketones for energy) or precoma (a state of near unconsciousness), renal (kidney) or hepatic (liver) impairment, acute conditions predisposing to renal impairment, cardiac or respiratory failure, recent myocardial infarction (heart attack), alcoholism and in patients with administration of iodinated contrast materials.

How To Use

This medicine should be taken with food.

Expert Advice

Avoid this medication if:

You are allergic to this medicine or its contents

Consult your doctor if:

You are pregnant, planning to have a child, or breastfeeding.
If you are avoiding unwanted pregnancy, so that your doctor may suggest a suitable form of birth control. Due to Metformin's effects on ovulation and pregnancy.
You have any sort of digestive problems after taking this medicine: Nausea, vomiting, diarrhea, etc.
You have a medical history of: Liver diseases, kidney diseases, congestive heart failure, or lung disease.
If you are about to undergo any medical or surgical treatment.
If you are about to undergo any CT scan, or X-ray, as it may interact with the dyes used in some pf these procedures.
If you have a B12 deficiency, are anemic, or are developing symptoms of anemia, Such as: lethargy, aches and pains, or a pale appearance to the skin.

Be careful about:

Having your meals on time to maintain blood sugar levels.
Taking the medicine timely, in the way that your physician has prescribed (with food), this will help avoid digestive disturbances.
Alcohol consumption.
Avoiding dehydration in any form.

Effective

Type II diabetes

What family of drugs does this medicine belong to?

It belongs to a class of drugs known as sulfonylureas. These drugs are used in the treatment of diabetes.

Can this medicine cause low blood sugar?

This is a possible side effect, but can be avoided if meals are taken regularly.

What do I do if I skip a dose?

If it has not been too long, have the skipped dose with your next meal. If it is almost time to take your next dose, do not take two doses, simply return to the prescribed routine.

What will happen if I skip a meal?

If you are not regular with your meals, you may experience symptoms of low blood sugar: Such as palpitation, sweating, dizziness, light headedness etc. In this case, taking sugar can relieve your symptoms.

Should this medicine be used beyond the date of expiry?

Kindly avoid taking any medication beyond the mentioned date of expiry.

Can this medicine be used if I have a liver or kidney disease?

No. Please consult your doctor if you suffer from a liver or a kidney disease.

Is this drug safe to use during pregnancy?

No. This drug is not recommended for use in pregnancy. Please consult your doctor before using it during pregnancy.

Can I use this drug during lactation?

No. The use of this medication is not recommended for use during lactation. Please consult your doctor before using this drug during breast feeding.

Can I use this drug with my blood pressure lowering medication?

Some of the blood pressure lowering drugs may enhance the effect of glibenclamide causing hypoglycemia. Please consult your doctor for further assistance.

Can I use this drug with insulin?

If your doctor has recommended using this drug with insulin then it should be added to your treatment. However, it is advised to strictly follow the prescribed doses , as failure to do may cause symptoms of hypoglycemia (low blood sugar) such as; dizziness, light headedness, palpitations etc.

Can this medicine be used in type 1 diabetes?

No. This medicine is only for use in type 2 diabetes.

Is it okay to use this drug in elderly?

Yes, this medicine can be given to elderly patients but regular dose monitoring is important because older patients are more prone to the development of low blood sugar. Please consult your doctor for further guidance.

What family of drugs does this medicine belong to?

Metformin belongs to a class of drugs known as biguanides. It is used to improve insulin activity, and control weight in diabetic patients. It is also known to regulate menstrual cycles (periods) and is used in the treatment of PCOs (Poly Cystic Ovarian Disease.)

Does this medicine contain hormones, or insulin?

No, this drug does not contain hormones, or insulin,. It enhances the effect of insulin, which helps patients with diabetes or PCOs, since their bodies tend to develop a resistance to the actions of insulin.

Can this drug be used with thyroid medications, and steroids?

Though there is no dangerous drug interaction, an adjustment in doses of both anti thyroid drugs, and steroids (eg: prednisone) may be required. It should be noted that patients taking steroids sometimes develop diabetes as a side effect. Please consult your physician, and discuss all the medicines you are taking, including their doses.

What is lactic acidosis and does this medication cause it?

Lactic acidosis is a very rare, and potentially fatal side effect of this medication. It occurs when there is an excessive buildup of lactic acid in the body. It may occur in patients who have overdosed. Symptoms include stomach problems, dizziness, breathing difficulty, muscle aches, irregular heartbeat, etc. Patients who experience these symptoms should go to a doctor immediately.

How long should I use this medication for?

Please use this medicine for the time that has been prescribed, and in the dose prescribed by your physician. Using it for longer than prescribed can cause side effects such as Vitamin B12 deficiency.

Can this medicine cause low blood sugar?

Low blood sugar is rare with Metformin, but it is a possible side effect, especially if you are taking other anti-diabetic drugs. Please maintain regularity in meals, dosage, and exercise to maintain blood sugar levels, and continue monitoring sugar levels. Also carry sugar or a sugary drink in case you feel dizzy, or develop any other sign of low blood sugar.

What do I do if I miss a dose?

You can take the missed dose as soon as you remember. If you remember when it is almost time for your next dose, then skip the missed dose entirely. Do not double your dose to catch up for missed doses.

What will happen if I skip a meal?

It is important to maintain regularity in meals, and exercise. Low blood sugar is rare, but may occur if you are taking other anti-diabetic medication.

Will this medicine make me loose or gain weight?

Weight gain is unlikely with this medicine, however, it does cause weight loss. This is because it improves the actions of insulin, and decreases hunger. Please take note that this drug is not a medicine which treats weight loss, and should only be used if prescribed by your physician. This medicine may, however, cause bloating. It is best taken after meals to avoid this side effect.

Can this medication cause any Vitamin deficiency or anemia?

This medication can result in a vitamin B12 deficiency after being used for a long time, and this can cause anemia. Please discuss with your doctor if you are already anemic, or if you start experiencing symptoms such as paleness, weakness, lethargy, etc.

Is it safe to use in patients with liver disease?

In patients who have fatty liver, and hepatitis C related liver disease, it is safe and is recommended. However, it is discouraged in patients who have liver cirrhosis, due to its association with lactic acidosis.

Pregnancy

Please consult your doctor before taking this medicne.

Lactation

Research suggests that this medicine should be avoided by women who are breastfeeding.

Driving

Please avoid driving when taking this medicine as it may affect your ability to drive.

Alcohol

Please avoid consuming alcohol when taking this medicine.

Precautions

Please consult your doctor as a precaution before taking this medicine if you have cross-sensivity to sulfonamides and sulfonamide derivative (type of antibiotic).

Pregnancy

This medicine is safe to use in pregnant females. No evidence of risk found.

Lactation

This medicine is contraindicated in lactating females.

Alcohol

Please avoid consuming alcohol when taking this medicine.

Precautions

Assess risk factors for lactic acidosis (buildup of lactate causing acidic pH of blood stream). Discontinue immediately if metabolic acidosis (overproduction of acid in the body) is suspected. Monitor renal (kidney) function at least annually. Discontinue the medicine for 48 hours before and after the elective surgery.

Related Lab Tests

Blood Glucose Fasting Lab Test
Insulin (Fasting) Lab Test
HbA1C (Glycosylated Hemoglobin) Lab Test

Disclaimer

Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.

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