Prescription Required
Primarily used for
Belongs to the category
Precaution:
Please regularly monitor blood glucose levels.
It is primarily indicated for treating Diabetes Mellitus type 2.
It Increases B cell insulin secretion, receptors and sensitivity. It also decreases the liver production of glucose
Strength: 3mg
Form: tablet
Dosing interval: 24 Hr
Maximum Dose: 8mg per day is well tolerated in many patients.
Dialyzable:Caution
It is suggested to start with 1-2mg initially, exceeding the doses to upto to 8mg per day
It is advised to monitor closely if the patient is having liver insufficiencies.
Evidence suggests that a dose of 1mg per day based on blood glucose level must be prescribed to patients with kidney impairment.
Can be used but doctor consultation is important before use, as human and animal research is insufficient or animals showed defects and human research hasn?t been conducted.
Insufficient data to prove if the drug enters breast milk, hence not recommended.
Kidney and liver insufficiency patients must be closely observed while taking Gliclazide, Any condition that causes stress and injury may create worsening conditions and patients have to withdraw or discontinue the therapy as well. Alcohol consumption may exaggerate the condition by causing intolerance reactions, close vigilance is suggested. Patients on alcohol should take extreme care because of their risk to develop glucose intolerance.
Time of onset: 1 Hr
Tmax: 9 Liters
Bioavailability: 100%
Protein Binding : 99.5%
Elimination Half Life (t1/2): 4 Hr (Mean)
Metabolism: The molecule has found to be extensively metabolized by liver
Volume of Distribution (Vd): 9 Liters
Active: Cyclohexyl hydroxy methyl derivative
Uses of MelitusThis medication is used for managing non-insulin dependent diabetes
Side effects of MelitusSome patients might experience hypoglycemia and liver failure. Please consult your doctor if you experience any of these symptoms.
When not to use MelitusPlease consult your doctor before taking this medication if you have any of these conditions; insulin-dependent diabetes mellitus (type of diabetes), or diabetic Ketoacidosis (diabetic complication).
How to take MelitusThis medicine should be taken with food.
Expert Advice for Melitus
Avoid this medication if:
Consult your doctor if:
Be careful about:
Please avoid driving when taking this medicine as it may affect your ability to drive.
Please avoid consuming alcohol when taking this medicine.
Research suggests that this medication should be avoided by pregnant women.
Research suggests this medication should be avoided by women who are breastfeeding.
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