Currently available in KARACHI only
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Prescription Required
It is primarily indicated for treating Diabetes Mellitus type 2.
It Increases B cell insulin secretion, receptors and sensitivity. It also decreases the liver production of glucose
Strength: 3mg
Form: tablet
Dosing interval: 24 Hr
Maximum Dose: 8mg per day is well tolerated in many patients.
Dialyzable:Caution
It is suggested to start with 1-2mg initially, exceeding the doses to upto to 8mg per day
It is advised to monitor closely if the patient is having liver insufficiencies.
Evidence suggests that a dose of 1mg per day based on blood glucose level must be prescribed to patients with kidney impairment.
Can be used but doctor consultation is important before use, as human and animal research is insufficient or animals showed defects and human research hasn?t been conducted.
Insufficient data to prove if the drug enters breast milk, hence not recommended.
Kidney and liver insufficiency patients must be closely observed while taking Gliclazide, Any condition that causes stress and injury may create worsening conditions and patients have to withdraw or discontinue the therapy as well. Alcohol consumption may exaggerate the condition by causing intolerance reactions, close vigilance is suggested. Patients on alcohol should take extreme care because of their risk to develop glucose intolerance.
Time of onset: 1 Hr
Tmax: 9 Liters
Bioavailability: 100%
Protein Binding : 99.5%
Elimination Half Life (t1/2): 4 Hr (Mean)
Metabolism: The molecule has found to be extensively metabolized by liver
Volume of Distribution (Vd): 9 Liters
Active: Cyclohexyl hydroxy methyl derivative
Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.
