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Primary Uses


Chronic stable angina, in coronary artery disease in patients with normal sinus rhythm who have a contraindication or intolerance to beta-blockers when monotherapy is inadequate and heart rate is > 60 beats per minute. Stable chronic heart failure with systolic dysfunction in patients with sinus rhythm with heart rate = 75 beats per minute in combination with standard therapy, including a beta-blocker, or when beta-blocker is contraindicated or not tolerated.

Side Effects

Luminous phenomena, blurred vision, bradycardia, 1st degree AV block, ventricular extra systole, blood pressure changes, headache, and dizziness.



Contraindicated in pregnancy


Contraindicated or not recommended


Mild to moderate hypotension, renal insufficiency (kidney dysfunction), moderate hepatic impairment (liver dysfunction). Monitor regularly for atrial fibrillation, QT syndrome or QT prolongation. Intraventricular conduction defects and ventricular dyssynchrony . Monitor BP after any treatment changes. heart failure. Retinitus pigmentosa. Elderly = 75yrs.


Pretreatment resting herat rate < 60 beats per minute. Persistent symptoms of bradycardia or if heart rate persisitently < 50 beats per minute. Cardiogenic shock, acute MI, severe hypotension (<90/50mmHg), sick sinus syndrome, sino-atral block, unstable or acute heart failure, pacemaker dependent, unstable angina, 2nd or 3rd degree AV block, cardiac arrhythmias, severe hepatic impairment, immediately after stroke.


What is this medicine used for?

It is a medicine used to prevent and treat heart-related chest pain (angina).

How does it help in relieving angina (chest pain)?

It reduces the risk of an angina attack by widening blood vessels and improving blood flow to the heart.

What should be the dose of this medicine?

Your doctor will decide the dose and how often you should take it. This may change from time to time depending on how well it is working.

Is it chewable?

No, it is not. It should be swallowed as a whole with water.

How to cope with its side effects?

To avoid the side effects from exaggerating, ensure to eat healthy, rest, avoid alcohol, drink plenty of fluids, and do not strain your eyes.


Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.


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