Sitagliptin is an oral anti-hyperglycemic medicine that belongs to the class of DPP-4 inhibitors. It is used to manage type II diabetes mellitus in adjunct to lifestyle changes. Diabetes is a chronic disease characterized by abnormally high levels of glucose in your blood. Type II diabetes is the most common form of diabetes where cells become resistant to insulin, leading to increased blood sugar. Sitagliptin increases the production of insulin and decreases the production of glucose.
Take this medicine by mouth with a glass of water.
Take this medicine with or without food, preferably with food.
Swallow it as a whole, do not crush or chew the medicine.
Take it at the same time to help you remember.
Or use it exactly as instructed by your doctor.
Expert Advice
Please take this medicine with or without meals.
Please consult your prescriber immediately if you experience trouble breathing, persistent abdominal pain, or any other adverse effects.
Dosage requires adjustment in case of trauma, surgery, and infection.
Please monitor glucose levels throughout use of this medicine.
Please ensure you tell your doctor you have diabetes before any surgery, getting medicine, etc.
Primary Uses
Type II diabetes
Indications
Monotherapy: This medicine is used for treating type 2 diabetes (condition characterized by elevated glucose levels) that is inadequately controlled by metformin, diet and exercise.
Dual therapy: It is used for treating diabetes type 2 along with metformin or a glitazone when patients respond inadequately to diet changes, exercise and either metformin or glitazine, or in combination with sulphonylureas in patients contraindicated for metformin, and for patients that do not respond adequately to sulphonylureas alone.
Triple therapy: This medicine is used with metformin and a sulphonylureas or glitazone for treating diabetes 2 that is inadequately controlled by dual therapy.
With insulin: This medicine is used with or without metformin for treating type 2 diabetes in patients who respond inadequately to diet, exercise, and insulin.
Side Effects
The patients administered with this medicine may experience pancreatitis (inflammation of pancreas), allergic reactions, Stevens-Jhonson Syndrome (allergic reaction), Hypoglycemia (low glucose levels), bullous pemphigoid (large fluid-filled blisters), osteoarthritis (weak bones), upper respiratory tract infections, flatulence, swelling, and influenza (flu-like symptoms).
Warnings
Pregnancy
During pregnancy, Sitagliptin should be used only when clearly needed. Consult your doctor for more information.
Lactation
Sitagliptin should be used cautiously in nursing females. Consult your doctor for more information.
Driving
This medicine might affect your driving ability if your blood sugar levels become too low. Avoid driving until your glucose levels are controlled.
Liver
Sitagliptin is probably safe to use in liver patients. Consult your doctor for more information.
Kidney
Sitagliptin should be used cautiously in kidney patients. Dose adjustment might be required. Consult your doctor for more information.
Alcohol
Alcohol consumption should be avoided during the course of treatment. It is considered unsafe. Consult your doctor for more information.
Precautions
Before using this medicine, inform your doctor about your complete medical history; especially of pancreatitis, kidney disease, heart failure, and gallstones.
Consult your doctor immediately if you develop symptoms of pancreatitis.
Inform your doctor about all your current medicines.
Do not quit this medicine without informing your doctor.
Do not share this medicine with anyone.
Do not double the dose, it may lead to severe hypoglycemia.
Contraindications
The patients with diabetic ketoacidosis (condition causing fat breakdown at an abnormal rate) and moderate to severe renal (kidney) impairment should avoid use of this medicine.
FAQS
Can this medicine cause low blood sugar?
This is a possible side effect, but can be avoided if meals are taken regularly. Try to carry sugar or a sugary drink in case you experience lightheadedness, or any other symptoms of low blood sugar. Take extra precautions during times of stress, or dehydration (fever, diarrhea etc.)
What do I do if I miss a dose?
You can take the missed dose as soon as you remember. If you remember when it is almost time for your next dose, then skip the missed dose entirely. Do not double your dose to catch up for missed doses.
What will happen if I skip a meal?
If you are not regular with your meals, you may experience symptoms of low blood sugar: Such as palpitation, sweating, dizziness, light headedness etc. In this case, taking sugar can relieve your symptoms.
Will this medicine make me gain or lose weight?
Weight gain is less likely with this drug.
Can this medicine cause disturbances in sleeping patterns, or stomach problems?
It is possible for patients to feel sleepy while taking this drug, and constipation is also a possible side effect.
Disclaimer
Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.
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