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This medicine is indicated in severe respiratory, genitourinary (urinary and genital system), bone, joint, abdominal infections, sepsis (life threatening condition in response to infection) and meningitis (inflammation of meninges).
GI upset, skin reactions, blood dyscrasias (blood disorders) are some of its side effects. It may rarely cause pseudomembranous colitis (inflammation of large intestine due to overgrowth of clostridium difficile bacteria), raised liver enzymes, glucosuria (glucose in urine), oliguria (urine output less than 1mL/kg/h), hematuria (blood in urine), bronchospasm (spasm of airways), phlebitis (inflammation of vein) at injection site, urinary and biliary precipitates, nephrolithiasis (kidney stones), pancreatitis (inflammation of pancreas), haemolytic anemia (red cells are destroyed faster than they are made), positive coombs test (test used to detect antibodies against the surface of red blood cells) etc.
This drug is contraindicated in patients with hypersensitivity to beta lactam drugs, in premature newborns having less than 41 weeks postmenstrual age; neonates over 41 weeks postmenstrual age with jaundice (a condition characterized by yellow discolouration of the skin, eyes and mucous membranes), hypoalbuminemia (low albumin levels) or acidosis (too much acid in body), concomitant treatment with IV calcium (including total parenteral nutrition containing calcium) in neonates over 41 weeks postmenstrual age - risk of precipitation in lungs and urine. It should not be used in hyperbilirubinemia (high bilirubin levels) neonates.
- This medication is to be administered by injection or infusion only.
- Contact prescriber if there is burning/swelling/redness/pain at injection or infusion or if there is rash, hives, itching, difficulty in breathing or swallowing, unrelieved diarrhea (watery stools), vaginal drainage or itching, mouth sores, blood, pus or mucus in stools or urine, easy bruising or bleeding, unusual chills or fever.
- Watery or bloody stools can occur 2 or more months after therapy and can be serious and require immediate treatment.
- Take sufficient amounts of fluids (2-3 liters per day) to maintain hydration, unless restricted by the prescriber.
Cefriaxone is used to treat certain bacterial infections.
It is contraindicated in hemolytic anemia (red cells are destroyed faster than they are made), diarrhea due to clostridium difficile bacteria, liver and gallbladder problems.
The average elimination half-life in healthy adults is 5.8–8.7 hours. In patients with renal impairment, the average elimination half-life increases to 11.4–15.7 hours.
1 gm ceftriaxone is dissolved in 10 ml of water. It is administered directly in vein over a period of 5 minutes.
It is used to treat gonorrhea (sexually transmitted disease), pelvic inflammatory disease (infection of female reproductive organs), meningitis (inflammation of meninges outside the brain and spinal cord).
There is no evidence of risk in pregnant females; therefore,caution is advised. Consult your doctor before the use of this medicine. 
There is no evidence of risk in lactating females; therefore, caution is advised. Consult your doctor before the use of this medicine. 
Patients with severe renal (kidney) and hepatic (liver) impairment and non severe hypersensitivity to other beta lactams are sensitive to the drug. Do not use it in pregnancy unless absolutely indicated. Full blood count should be monitored during prolonged treatment. Disclaimer
Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.
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