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Rs. 87.98
Rs 103.50

Rs.17.6/tablet

5 tablet(s)/Strip

Pack Size : 10's tablet

Rs.207 Total

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Prescription Required

Valiant-M 850mg/50mg tablet

Valiant-M 850mg/50mg tablet is composed of

Metformin (850mg)
Vildagliptin (50mg)

Primarily used for

Type 2 diabetes

Belongs to the category

Hypoglycemics

Precaution:

Assess risk factors for lactic acidosis (buildup of lactate causing acidic pH of blood stream). Discontinue immediately if metabolic acidosis (overproduction of acid in the body) is suspected. Monitor renal (kidney) function at least annually. Discontinue the medicine for 48 hours before and after the elective surgery. 

Patients with moderate to severe renal (kidney) impairment, who are allergic to vildagliptin and patients with heart failure are sensitive to the medicine; in moderate to severe heart failure patients it should be avoided.  Elderly patients who are taking vildagliptin, their liver functioning should be monitored. There may be a risk of pancreatitis (inflammation of pancreas); advise patients of symptoms and discontinue if suspected.

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Vildagliptin + Metformin

Indication

It is primarily indicated for treating Diabetes Mellitus type 2 in people who are unable to respond to a monotherapy.

Dosage

Strength: 850mg/50mg

Form: tablet

Dosing interval: 24 Hr

Maximum Dose: Vildagliptin: The drug must not surpass a dose of 100mg per day. Metformin: 2000mg per day

Maintainance dose

A dose of 50/1000mg once daily can be initiated then adjusted accordingly

Hepatic Adjustment

The medication is not prescribed in patients with hepatic impairments. Also carefully monitor ALT (Alanine aminotransferase) and AST (Aspartate aminotransferase) values; and adjust accordingly if found to be x2.5 upper limit normal (ULN).

Renal Adjustment

Adjust the dose if Creatinine clearence of the patient is greater then 1.5mg/dl in males and 1.4mg/dl in females.

  • pregnant

    Pregnancy

    Can be used but doctor consultation is important before use, as human and animal research is insufficient or animals showed defects and human research hasn?t been conducted.

  • mother

    Lactation

    The data for vildagliptin and metformin combination medicine for, if it enters breast milk, is not known. It should not be used.

ContraIndication
Cautions

Studies have reported a decreased Vitamin B12 levels in patients taking metformin or combination therapy. Patients with compromised renal and liver functions should be monitored closely. Hypoglycemic conditions have been reported with worsening of conditions when using a combination of antidiabetic therapy. Stress aur traumatized patients should be monitored closely. Patients taking vildagliptin and metformin should be asked to stop the use of alcohol.

Pharmacokinetics

usesUses of Metformin

This medicine is indicated in maturity onset diabetes either alone or with sulphonylureas. It is also used as adjuvant therapy in insulin dependent diabetes, particularly in obese patients.

side-effectsSide effects of Metformin

GI upset, taste disturbance, abnormal liver function tests, hepatitis (inflammatory condition of liver), skin reactions, reduced B12 absorption are some of its side effects. Rarely it may cause lactic acidosis (buildup of lactate causing acidic pH of blood stream).

pillsWhen not to use Metformin

This medicine is contraindicated in patients with diabetic ketoacidosis (life threatening condition in which liver breaks down fats into ketones for energy) or precoma (a state of near unconsciousness), renal (kidney) or hepatic (liver) impairment, acute conditions predisposing to renal impairment, cardiac or respiratory failure, recent myocardial infarction (heart attack), alcoholism and in patients with administration of iodinated contrast materials.

food-pillsHow to take Metformin

This medicine should be taken with food.

usesUses of Vildagliptin

This medicine is indicated in type 2 diabetes (a disorder characterized by high sugar levels in blood), in combination with pioglitazone or metformin or sulphonylureas.

side-effectsSide effects of Vildagliptin

Bullous (pus filled injury) and exfoliative (injury characterized with shedding of skin) lesions. When taken alone it can cause dizziness; when taken with metformin it can cause tremors (shaking movements), headache, nausea (an urge to vomit), hypoglycaemia (low sugar levels); when taken with sulphonylurea it can cause tremors (shaking movements), headache, nausea (an urge to vomit), asthenia (physical weakness), hypoglycaemia (low sugar levels); when taken with a glitazone it can cause weight gain and peripheral edema (swelling of hands and feet) and with insulin it can cause headache, hypoglycaemia (low sugar levels), GI upset, chills etc.

pillsWhen not to use Vildagliptin

This medicine is contraindicated in diabetic ketoacidosis (a life threatening condition in which liver breaks down fats into ketones for energy), hepatic (liver) impairment and congestive heart failure (a condition that progresses over a long time and affects the pumping of heart).

pills Expert Advice for Metformin

Avoid this medication if:

  • You are allergic to this medicine or its contents 

Consult your doctor if:

  • You are pregnant, planning to have a child, or breastfeeding.
  • If you are avoiding unwanted pregnancy, so that your doctor may suggest a suitable form of birth control. Due to Metformin's effects on ovulation and pregnancy.
  • You have any sort of digestive problems after taking this medicine: Nausea, vomiting, diarrhea, etc.
  • You have a medical history of: Liver diseases, kidney diseases, congestive heart failure, or lung disease.
  • If you are about to undergo any medical or surgical treatment. 
  • If you are about to undergo any CT scan, or X-ray, as it may interact with the dyes used in some pf these procedures.
  • If you have a B12 deficiency, are anemic, or are developing symptoms of anemia, Such as: lethargy, aches and pains,  or a pale appearance to the skin. 

Be careful about:

  • Having your meals on time to maintain blood sugar levels.
  • Taking the medicine timely, in the way that your physician has prescribed (with food), this will help avoid digestive disturbances.
  • Alcohol consumption.
  • Avoiding dehydration in any form.

pills Expert Advice for Vildagliptin

  • Take with or without meals.

  • Take the prescribed diet, exercise regularly and control weight.

  • Check blood glucose periodically.

  • Report persistent dizziness, headache, hypoglycaemia (low sugar levels).

Q: What family of drugs does this medicine belong to?
Q: Does this medicine contain hormones, or insulin?
Q: Can this drug be used with thyroid medications, and steroids?
Q: What is lactic acidosis and does this medication cause it?
Q: How long should I use this medication for?
Q: Can this medicine cause low blood sugar?
Q: What do I do if I miss a dose?
Q: What will happen if I skip a meal?
Q: Will this medicine make me loose or gain weight?
Q: Can this medication cause any Vitamin deficiency or anemia?
Q: Is it safe to use in patients with liver disease?
Q: Can this drug be linked with pancreatitis?
Q: Can this medicine cause low blood sugar?
Q: What do I do if I miss a dose?
Q: Can this drug cause cough, or stomach problems?
Q: Should this medicine be used beyond the date of expiry?

Warnings

  • wine-bottle

    Alcohol

    Metformin

    Please avoid consuming alcohol when taking this medicine.

    Vildagliptin

    Please avoid consuming alcohol when taking this medicine.

  • pregnant

    Pregnancy

    Metformin

    This medicine is safe to use in pregnant females. No evidence of risk found. 

    Vildagliptin

    This medication is contraindicated in pregnancy. Consult your physician

  • mother

    Breast Feeding

    Metformin

    This medicine is contraindicated in lactating females.

    Vildagliptin

     

    This medication is contraindicated. Consult your physician before breastfeeding.

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