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Vildagliptin + Metformin

Indication

It is primarily indicated for treating Diabetes Mellitus type 2 in people who are unable to respond to a monotherapy.

Dosage

Strength: 850mg/50mg

Form: tablet

Dosing interval: 24 Hr

Maximum Dose: Vildagliptin: The drug must not surpass a dose of 100mg per day. Metformin: 2000mg per day

Maintainance dose

A dose of 50/1000mg once daily can be initiated then adjusted accordingly

Hepatic Adjustment

The medication is not prescribed in patients with hepatic impairments. Also carefully monitor ALT (Alanine aminotransferase) and AST (Aspartate aminotransferase) values; and adjust accordingly if found to be x2.5 upper limit normal (ULN).

Renal Adjustment

Adjust the dose if Creatinine clearence of the patient is greater then 1.5mg/dl in males and 1.4mg/dl in females.

  • pregnant

    Pregnancy

    Can be used but doctor consultation is important before use, as human and animal research is insufficient or animals showed defects and human research hasn?t been conducted.

  • mother

    Lactation

    The data for vildagliptin and metformin combination medicine for, if it enters breast milk, is not known. It should not be used.

ContraIndication
Cautions

Studies have reported a decreased Vitamin B12 levels in patients taking metformin or combination therapy. Patients with compromised renal and liver functions should be monitored closely. Hypoglycemic conditions have been reported with worsening of conditions when using a combination of antidiabetic therapy. Stress aur traumatized patients should be monitored closely. Patients taking vildagliptin and metformin should be asked to stop the use of alcohol.

Pharmacokinetics

Disclaimer

Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.

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