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Rs. 163.63
Rs 192.50

Rs.27.5/tablet

7 tablet(s)/Strip

Pack Size : 28 Tablets

Rs.770 Total

Vilget 50mg tablet

Vilget 50mg tablet is composed of

Vildagliptin (50mg)

Primarily used for

Type 2 diabetes

Precaution:

Please monitor liver function in elderly patients.

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For Medical Professionals

Vildagliptin C17H25N3O2

Molecular Weight: 303g/mol
Dissociation Constant: 14.7
Indication

It is primarily indicated for treating Diabetes Mellitus type 2.

Mechanism of Action

It is known to be a cyanopyrrolidone based derivative which is responsible for inhibition of dipeptidyl peptidase (DDP4) causing the release of insulin via beta islet cells and reduction of glucagon release via alpha islet cells of pancreas.

Dosage

Strength: 50mg

Form: tablet

Dosing interval: 12 hr or 24 Hr

Maximum Dose: 100 mg, more than 100mg not recommended.

Dialyzable:Not dialyzable.

Maintainance dose

When used in monotherpay with metformin, Vildagliptin is prescribed as 50mg twice a day. When used along with sulfonylureas, vildagliptin is prescribed as 50mg once in the morning

Hepatic Adjustment

The medication is not prescribed in patients with hepatic impairments. It is advised to closely monitor the ALT (Alanine aminotransferase) and AST (Aspartate aminotransferase) values and adjust accordingly if found to be x3 upper limit normal (ULN).

Renal Adjustment

Patients with Creatinine clearence less than 50ml/min are recommended with a dose of 50mg once a day.

  • pregnant

    Pregnancy

    Doctor consultation is important before use, as human and animal research is insufficient or animals showed defects and human research hasn?t been conducted.

  • mother

    Lactation

    The data for vildagliptin if it enters breast milk; is not known. It should not be used.

ContraIndication
Cautions

End stage renal diseased patients should use this medicine with great care. Type 1 Diabetes and diabetic ketoacidosis suffering patients must also monitor therapy goals. Acute pancreatitis. Cardiovascular diseases like congestive heart faliures. Skin disorders such as blisters.

Pharmacokinetics

Time of onset: The drug shows a delayed onset of action when administered with meals

Tmax: 71 Liters

Bioavailability: More than 90%

Protein Binding : 9.3%

Elimination Half Life (t1/2): 1.5 Hr

Metabolism: It has been reported to primarily metabolise through liver.

Volume of Distribution (Vd): 71 Liters

Metabolites:

Metabolite LAY151 is formed which is pharmacologically inactive.

Medicine Overview of Vilget 50mg tablet

usesUses of Vilget

Vilget is used in the management of type 2 diabetes.

side-effectsSide effects of Vilget

Some patients might experience Nausea, Oedema (swelling) or Headache. Please consult your doctor if you experience any of these symtpoms

pillsWhen not to use Vilget

Please consult your doctor before taking Vilget if you have Ketoacidosis (diabetes complication).

Warnings

  • drive

    Driving

    Please avoid driving when taking this medicine as it may affect your ability to drive.

  • wine-bottle

    Alcohol

    Please avoid consuming alcohol when taking this medicine.

  • pregnant

    Pregnancy

    Research suggests that Vilget should be avoided by pregnant women.

  • mother

    Breast Feeding

    Research suggests that Vilget should be avoided by women who are breastfeeding.

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