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This medicine is used to treat hypertension (high Blood pressure), myocardial ischemia (decreased blood supply to heart muscle) associated with stable (chest pain triggered by activity), or vasospastic angina (chest pain triggered with vasospasm of coronary artery).

 

 

Patients using this medicine may commonly experience headache, edema, fatigue, nausea, dizziness (lightheadedness), flushing (reddening of the skin), rashes, and gingival hyperplasia (overgrowth of gum). Patients may rarely experience alopecia (spot baldness), pruritus (itching), abdominal and back pain, hyperglycemia, increased urination, palpitations, and GI (stomach) upset. 

This medicine is contraindicated in patients having history of cardiogenic shock (inability of heart to pump enough blood), aortic stenosis (narrowing of aortic valve opening), unstable angina (chest pain triggered by minimum or no activity), severe hypotension, unstable heart failure following MI, and hypersensitivity to dihydropyridines.

 

  1. What is the best time to take this medicine?

It does not matter what time of day you take this medicine (morning or evening) but it is best to take it at the same time every day when you are most likely to remember, for more even blood levels and therefore effectiveness.

 

  1. What to avoid while taking this medicine?

Do not eat or drink lots of grapefruit or grapefruit juice. This is because grapefruit can increase the concentration of drug in your body and worsen side effects.

 

  1. Is this medicine harmful to kidneys?

This medicine should not cause kidney damage and is used to treat high blood pressure and slow the progression of chronic kidney disease.

 

  1. Is this medicine safe to use?

It is generally a safe and effective drug, but it may cause side effects in some people.

 

 

  1. How to take this medicine?

Swallow the tablet with a drink of water. You can take this medicine before or after meals.

  • Take with or without meals.
  • To avoid stomachache, take with meals.
  • Take missed dose as soon as you remember and next dose in 24 hours.
  • Contact prescriber if there is unrelieved headache, vomiting, weight gain, palpitations, or difficulty in breathing.
  • Check blood pressure regularly.

 

Angina and Hypertension

This medication is used in the treatment of hypertension (increased blood pressure) as well as cardiovascular (heart and blood vessels) related events in patients with established atherosclerotic (hardening of blood vessels ) cardiovascular( heart and blood vessels ) disease. It is also used in patients with type 2 diabetes. With end organ damage.

Patients using this medication may at times experience upper respiratory tract infections, back pain, and sinusitis. If you experience any of these symptoms for a prolonged period of time, please consult your doctor.

This medication is not recommended in patients with severe hepatic (liver) impairment and various other disorders of the gallbladder.  It is also contraindicated in patients with hypercalcemia (high blood calcium ) and refractory hypokalemia (low blood potassium). For further details , consult your healthcare provider.

INDICATIONS

 

This medication is used in the treatment of hypertension (increased blood pressure) as well as cardiovascular (heart and blood vessels) related events in patients with established atherosclerotic (hardening of blood vessels ) cardiovascular( heart and blood vessels ) disease. It is also used in patients with type 2 diabetes. With end organ damage.

 

CONTRAINDICATIONS

 

This medication is not recommended in patients with severe hepatic (liver) impairment and various other disorders of the gallbladder.  It is also contraindicated in patients with hypercalcemia (high blood calcium ) and refractory hypokalemia (low blood potassium). For further details , consult your healthcare provider.

 

 

PRECAUTIONS

 

This medication should be used with extreme caution in patients with impaired hepatic (liver) function, and bilateral renal artery stenosis (narrowing of arteries supplying the kidneys).  Mild to moderate renal(kidney ) impairment.  It may also impair glucose tolerance . Patients with renovascular (blood vessels of the kidney) hypertension (high blood pressure) as well as elderly patients should be cautioned against the use of this medication.

 

 

SIDE EFFECTS

 

The patients administered with this medicine may experience respiratory tract infections, back pain, sinusitis (sinus infection), diarrhea, flu-like-symptoms, pharyngitis (inflammation of pharynx), weakness, fever, hyperkalemia (increased potassium levels), hypotension (low blood pressure), renal (kidney) failure, glaucoma (increased pressure in eye), and heart problems.

 

PREGNANCY

 

This medication should not be used in pregnancy.

 

LACTATION

 

This medication should not be used by lactating mothers.

Hypertension
As per FDA recommendation, simvastatin dosage should be limited to 20 mg daily while taking amlodipine. Also, all the CYP3A4 enzyme inhibitors like diltiazem, ketoconazole, itraconazole & ritonavir should be avoided while taking amlodipine.
You don’t need to worry about the swelling, as it is one of the very common adverse effects of the drug. This will go off once you withdraw its use. But you still need to consult your physician if the condition is getting worse.
You are not advised to do so abruptly nor are you supposed to make this decision by yourself. Consult with your physician, who will most probably advise for a gradual withdrawal. This is done to avoid the chest pain and relapse of high blood pressure, which is usually observed in such scenarios.
It is available in tablet, drops and I/V (intravenous) forms.
No, the drug is not safe for any kind of kidney or liver disease. Consult your physician for an alternative.
It doesn’t really matter at what time of the day you take amlodipine, but it is best to take it at the exact time every day, for more even blood levels & more effectiveness of the medicine.
New research shows that administering blood pressure medicines at bedtime effectively helps to reduce your risk of illness or death due to blood vessel & heart disease. Timings are important as BP follows a daily rhythm. It is high during the day & falls at nighttime.
It is seen that titration of amlodipine from 5-10 mg every day in patients not responding to the treatment with 5 mg dose showed significant decrease in BP.
This medication is used for treating hypertension (high blood pressure), cardiovascular (involving the heart and its blood vessels) events in patients with atherosclerotic disease (plaque build-up inside arteries), and type 2 diabetes mellitus (disease characterized by glucose impairment) with specific organ damage.
Please store this medicine at room temperature (18-25 Celsius). Keep medicine away from children, and excessive light and moisture. Read the leaflet provided with the medicine for further storage guidance.
This medicine is not recommended for pregnant females. This medicine is not recommended for nursing females.
The patients administered with this medicine may experience respiratory tract infections, back pain, sinusitis (sinus infection), diarrhea, flu-like-symptoms, pharyngitis (inflammation of pharynx), weakness, fever, hyperkalemia (increased potassium levels), hypotension (low blood pressure), renal (kidney) failure, glaucoma (increased pressure in eye), and heart problems.
The patients with impaired hepatic (liver) and renal (kidney) function, heart abnormalities, electrolyte disturbances, dietary salt restriction, primary aldosteronism (increase in aldosterone levels), and elderly should use this medicine cautiously.
This medicine is mostly taken orally. The dosage is dependent on the severity of condition and response to treatment. Please consult your doctor before use.
The patients with hepatic (liver) disorders and impairment e.g. cholestasis (reduction or stoppage of bile flow), refractory hypokalemia (decreased potassium levels), and hypercalcemia (increased calcium levels) should avoid use of this medicine.
This medicine is not safe to be administered in pregnant females. Consult your doctor for more information.
This medicine is not recommended for lactating females.
Please avoid driving when taking this medicine as it may affect your ability to drive.
This medication should be used with caution in patients who recently had MI (heart attack), or have history of impaired hepatic (liver) function, hypertensive crisis, and heart failure.
This medication should not be used in pregnancy.
This medication should not be used by lactating mothers. Consult your doctor if there's no other alternative medicine.
Please avoid driving when taking this medicine as it may affect your ability to drive.
Please avoid consuming alcohol when taking this medicine.
This medication should be used with extreme caution in patients with impaired hepatic (liver) function, and bilateral renal artery stenosis (narrowing of arteries supplying the kidneys).  Mild to moderate renal(kidney ) impairment.  It may also impair glucose tolerance . Patients with renovascular (blood vessels of the kidney) hypertension (high blood pressure) as well as elderly patients should be cautioned against the use of this medication.

Disclaimer

Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.

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