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This medicine is used in the treatment of severe malaria including cerebral malaria and as a second line treatment in chloroquine resisitant falciparum malaria.

Patients using this medication may at times experience abdominal pain, anorexia (eating disorder), diarrhea, vomiting, nausea, and dizziness. If you experience any of these symptoms for a long period of time, consult your doctor immediately.

This medicine should not be used in patients with history of arrhythmias (abnormal heart rhythm), bradycardia (slow heartrate), and congestive heart failure.

This medicine should be taken with food.

Indication:

This medication is used to treat severe malaria  including cerebral malaria and as a second line treatment in chloroquine resisitant falciparum malaria

Contraindication:

This medication is contraindicated in patients with history of arrhythmias (abnormal heart rhythm), bradycardia (slow heart rate), and congestive heart failure

Side effects:

The patients taking this medication may experience abdominal pain, anorexia (eating disorder), diarrhea, vomiting, nausea, and dizziness. If you experience any of these symptoms for a long period of time, consult your doctor immediately

Precautions:

The patients taking this medication must be cautious in cases of electrolyte disturbance, use with other drug that causes prolonged QT interval (heart muscles take longer than usual to recharge between beats), dizziness, severe cardiac (heart) or renal (kidney) impairment

Interaction:

This medication may interact with inhibitors of CYP3A4, substrates of CYP262D, grapefruit juice, class Ia III antiarrythmics (prevents abnormal heart rhythm), antidepressants, antimalarials, gormonal contraceptives, azole anti-fungal and antipsychotics (treats bipolar disorder)

Pregnancy:

This medication is contraindicated in pregnancy 

Lactation:

This medication is contraindicated in lactation         

Malaria
This medicine is used to treat severe malaria including cerebral malaria (malaria involving the brain) and Chloroquine-resistant Falciparum Malaria (species of plasmodium).
Please store the tablet form of this medicine at room temperature (18-25 Celsius). Keep medicine away from children, and excessive light and moisture.
The patients with heart problems and family history of sudden death should be cautious.
This medicine is not recommended during pregnancy. The effect is undetermined in lactating females; therefore, caution is advised.
You may experience reticulocytopenia (decrease in immature red blood cells), heart problems, abdominal pain, and diarrhea.
This medicine is mostly used intravenously. It is injected into a vein by a medical professional. However, if you are self-injecting or using it at home, make sure you take all necessary precautions before injecting. The dosage is dependent on the age, condition and its severity. Please consult your doctor before use.
The patients with electrolyte disturbances and using other medicines for severe heart problems should avoid use of this medicine.
This medicine is contrainicated in pregnant females.
This medication is contraindication in lactating females.
Please avoid consuming alcohol when taking this medicine.
This medicine should be used with extreme caution in patients with an electrolye disturbance and in those who use other drugs known to cause QT-interval prolongation.

Disclaimer

Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.

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