Amlodipine is an oral antihypertensive medicine that belongs to the class of calcium channel blockers. It works by relaxing the blood vessels to allow easy flow of blood. Amlodipine is used alone or in combination with other medicines to manage high blood pressure and coronary artery disease. Antianginal effects of this medicine controls chest pain (angina). Hypertension is a common disease in which the blood pressure in arteries is so high that your heart has to work more than normal. Continuous high blood pressure will eventually cause serious health problems like heart attack, stroke, or kidney failure.
Swallow it as a whole, do not crush or chew the medicine.
Take it at the same time to help you remember.
Or use it exactly as instructed by your doctor.
Take with or without meals.
To avoid stomachache, take with meals.
Take missed dose as soon as you remember and next dose in 24 hours.
Contact prescriber if there is unrelieved headache, vomiting, weight gain, palpitations, or difficulty in breathing.
Check blood pressure regularly.
Angina and Hypertension
This medicine is used to treat hypertension (high blood pressure), myocardial ischemia (decreased blood supply to heart muscle) associated with stable (chest pain triggered by activity), or vasospastic angina (chest pain triggered with vasospasm of coronary artery).
Patients using this medicine may commonly experience headache, edema, fatigue, nausea, dizziness (lightheadedness), flushing (reddening of the skin), rashes, and gingival hyperplasia (overgrowth of gum). Patients may rarely experience alopecia (spot baldness), pruritus (itching), abdominal and back pain, hyperglycemia, increased urination, palpitations, and GI (stomach) upset.
This medicine is not safe to be administered in pregnant females. Consult your doctor for more information.
This medicine is not recommended for lactating females. Consult your doctor for better advice.
This medicine doesn’t usually affect your driving ability. However, avoid driving until you know how this medicine affects you.
Use this medicine cautiously in liver patients. Dose adjustment is required. Consult your doctor for more information.
Use this medicine cautiously in kidney patients. No dose adjustment is required. Consult your doctor for more information.
Avoid alcohol consumption when using this medicine. Consult your doctor for more information.
Before using this medicine, inform your doctor about your complete medical history; especially of heart disease, liver disease, or low blood pressure.
Inform your doctor about all your current medicines.
Do not quit this medicine without informing your doctor.
Do not share this medicine with anyone.
This medicine is contraindicated in patients having history of cardiogenic shock (inability of heart to pump enough blood), aortic stenosis (narrowing of aortic valve opening), unstable angina (chest pain triggered by minimum or no activity), severe hypotension, unstable heart failure following MI, and hypersensitivity to dihydropyridines.
Which medicines should be avoided with Amlodidpine?
As per FDA recommendation, simvastatin dosage should be limited to 20 mg daily while taking amlodipine. Also, all the CYP3A4 enzyme inhibitors like diltiazem, ketoconazole, itraconazole & ritonavir should be avoided while taking amlodipine.
I have been experiencing swelling in hands and foot since I started using the medicine. I amconcerned whether this swelling will persist?
You don’t need to worry about the swelling, as it is one of the very common adverse effects of the drug. This will go off once you withdraw its use. But you still need to consult your physician if the condition is getting worse.
When is it safe to discontinue the medicine?
You are not advised to do so abruptly nor are you supposed to make this decision by yourself. Consult with your physician, who will most probably advise for a gradual withdrawal. This is done to avoid the chest pain and relapse of high blood pressure, which is usually observed in such scenarios.
In what forms is the medicine available?
It is available in tablet, drops and I/V (intravenous) forms.
I am a patient of dialysis and have a history of getting treated for hepatitis C too. So, is the medicine safe for me?
No, the drug is not safe for any kind of kidney or liver disease. Consult your physician for an
What is the best time to take this medicine?
It doesn’t really matter at what time of the day you take amlodipine, but it is best to take it at the exact time every day, for more even blood levels & more effectiveness of the medicine.
Why taking this medicine at night is useful?
New research shows that administering blood pressure medicines at bedtime effectively helps to reduce your risk of illness or death due to blood vessel & heart disease. Timings are important as BP follows a daily rhythm. It is high during the day & falls at nighttime.
How much does this medicine help reduce blood pressure?
It is seen that titration of amlodipine from 5-10 mg every day in patients not responding to the treatment with 5 mg dose showed significant decrease in BP.
This medication is used for treating hypertension (high blood pressure), cardiovascular (involving the heart and its blood vessels) events in patients with atherosclerotic disease (plaque build-up inside arteries), and type 2 diabetes mellitus (disease characterized by glucose impairment) with specific organ damage.
Please store this medicine at room temperature (18-25 Celsius). Keep medicine away from children, and excessive light and moisture.
Read the leaflet provided with the medicine for further storage guidance.
Effects on pregnancy and lactation:
This medicine is not recommended for pregnant females.
This medicine is not recommended for nursing females.
The patients administered with this medicine may experience respiratory tract infections, back pain, sinusitis (sinus infection), diarrhea, flu-like-symptoms, pharyngitis (inflammation of pharynx), weakness, fever, hyperkalemia (increased potassium levels), hypotension (low blood pressure), renal (kidney) failure, glaucoma (increased pressure in eye), and heart problems.
The patients with impaired hepatic (liver) and renal (kidney) function, heart abnormalities, electrolyte disturbances, dietary salt restriction, primary aldosteronism (increase in aldosterone levels), and elderly should use this medicine cautiously.
This medicine is mostly taken orally. The dosage is dependent on the severity of condition and response to treatment. Please consult your doctor before use.
The patients with hepatic (liver) disorders and impairment e.g. cholestasis (reduction or stoppage of bile flow), refractory hypokalemia (decreased potassium levels), and hypercalcemia (increased calcium levels) should avoid use of this medicine.
Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.
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