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This medicine is used to treat hypertension (high Blood pressure), myocardial ischemia (decreased blood supply to heart muscle) associated with stable (chest pain triggered by activity), or vasospastic angina (chest pain triggered with vasospasm of coronary artery).

 

 

Patients using this medicine may commonly experience headache, edema, fatigue, nausea, dizziness (lightheadedness), flushing (reddening of the skin), rashes, and gingival hyperplasia (overgrowth of gum). Patients may rarely experience alopecia (spot baldness), pruritus (itching), abdominal and back pain, hyperglycemia, increased urination, palpitations, and GI (stomach) upset. 

This medicine is contraindicated in patients having history of cardiogenic shock (inability of heart to pump enough blood), aortic stenosis (narrowing of aortic valve opening), unstable angina (chest pain triggered by minimum or no activity), severe hypotension, unstable heart failure following MI, and hypersensitivity to dihydropyridines.

 

  1. What is the best time to take this medicine?

It does not matter what time of day you take this medicine (morning or evening) but it is best to take it at the same time every day when you are most likely to remember, for more even blood levels and therefore effectiveness.

 

  1. What to avoid while taking this medicine?

Do not eat or drink lots of grapefruit or grapefruit juice. This is because grapefruit can increase the concentration of drug in your body and worsen side effects.

 

  1. Is this medicine harmful to kidneys?

This medicine should not cause kidney damage and is used to treat high blood pressure and slow the progression of chronic kidney disease.

 

  1. Is this medicine safe to use?

It is generally a safe and effective drug, but it may cause side effects in some people.

 

 

  1. How to take this medicine?

Swallow the tablet with a drink of water. You can take this medicine before or after meals.

  • Take with or without meals.
  • To avoid stomachache, take with meals.
  • Take missed dose as soon as you remember and next dose in 24 hours.
  • Contact prescriber if there is unrelieved headache, vomiting, weight gain, palpitations, or difficulty in breathing.
  • Check blood pressure regularly.

 

Angina and Hypertension

This medication is used for lowering blood pressure in hypertensive (increased blood pressure) patients and for treating edema (excess fluid in the body) associated with heart disease. It can also be used to treat Nephrotic Syndrome.

Patients using this medication may at times experience dizziness, headache, edema (collection of body fluid in tissues and body cavities), and fatigue. If you experience any of these symptoms for a prolonged period of time, please consult your doctor.

This medicine is contraindicated in patients suffering from renal (kidney) decompensation and anuria (non-passage of urine).

  • Take with meals.
  • Change position slowly.
  • Include potassium rich foods in diet such as bananas and orange juice.
  • If you have diabetes, check blood sugar level regularly and inform prescriber about changes.
Hypertension

This medicine is used to treat hypertension (high blood pressure), heart failure, myocardial infarction (Heart attack) with left ventricular failure or left ventricular diastolic failure.

Patients using this medicine may rarely experience syncope (fainting), thrombocytopenia (low levels of platelets), renal (kidney) dysfunction, angioedema (swelling under skin or mucous membrane), dizziness (lightheadedness), and hypotension.

This medicine is contraindicated in patients with severe hepatic (liver) impairment, cirrhosis (irreversible scarring of liver), biliary (bile duct) obstruction, cholestasis (decrease in bile flow), and primary hyperaldosteronism (excessive aldosterone production).

  • Take the medicine at the same time each day, with or without meals.
  • Contact prescriber if there is chest pain, palpitations, swelling of face/ankle/tongue, unrelieved headache, weakness, difficulty in breathing, or unusual cough.
  • Do not take potassium supplements or salt substitutes.
  • Change body position slowly.
Hypertension
As per FDA recommendation, simvastatin dosage should be limited to 20 mg daily while taking amlodipine. Also, all the CYP3A4 enzyme inhibitors like diltiazem, ketoconazole, itraconazole & ritonavir should be avoided while taking amlodipine.
You don’t need to worry about the swelling, as it is one of the very common adverse effects of the drug. This will go off once you withdraw its use. But you still need to consult your physician if the condition is getting worse.
You are not advised to do so abruptly nor are you supposed to make this decision by yourself. Consult with your physician, who will most probably advise for a gradual withdrawal. This is done to avoid the chest pain and relapse of high blood pressure, which is usually observed in such scenarios.
It is available in tablet, drops and I/V (intravenous) forms.
No, the drug is not safe for any kind of kidney or liver disease. Consult your physician for an alternative.
It doesn’t really matter at what time of the day you take amlodipine, but it is best to take it at the exact time every day, for more even blood levels & more effectiveness of the medicine.
New research shows that administering blood pressure medicines at bedtime effectively helps to reduce your risk of illness or death due to blood vessel & heart disease. Timings are important as BP follows a daily rhythm. It is high during the day & falls at nighttime.
It is seen that titration of amlodipine from 5-10 mg every day in patients not responding to the treatment with 5 mg dose showed significant decrease in BP.
It is used in the management of increased blood pressure. It does so by acting on the kidneys.
Yes, an increased urinary flow is observed.
No, it is not. But if increased blood pressure is posing any painful effect on the body, this medicine’s effect might decrease pain effect secondarily.
No, you should have a normal diet. This is so because one loses a lot of sodium through urine while using this medicine, so a complete healthy meal is a compulsion.
No research or complaint regarding this issue came across as yet. But it is advised to talk to your physician for further queries.
This medication works by relaxing the blood vessels so that blood can flow easily.
Try to take this medication same time everyday?
If this medication continues for a long time, it may damage the blood vessels of heart and kidneys.
Avoid potassium-rich foods like bananas, oranges, and green leafy vegetables as this medicine already raises potassium concentrations in the body.
Yes, this medicine might make you sleepy. Using alcohol along with this medicine will worsen the symptom. Avoid driving.
This medicine should not be given to a child younger than 6 years.
This medicine is not safe to be administered in pregnant females. Consult your doctor for more information.
This medicine is not recommended for lactating females.
Please avoid driving when taking this medicine as it may affect your ability to drive.
This medication should be used with caution in patients who recently had MI (heart attack), or have history of impaired hepatic (liver) function, hypertensive crisis, and heart failure.
This medication should not be used in pregnancy.
This medication should not be used by lactating mothers. Consult your doctor if there's no other alternative medicine.
Please avoid driving when taking this medicine as it may affect your ability to drive.
Please avoid consuming alcohol when taking this medicine.
Avoid this medicine in severe renal (kidney) disease. Patients suffering from gout (painful joints), diabetes (raised blood sugar level), and moderate to high cholesterol concentration should stay cautious.
This medicine should is contraindicated in pregnant females. 
This medicine should not be used by lactating mothers. Consult your doctor.
Please avoid driving when taking this medicine as it may affect your ability to drive.
Please avoid consuming alcohol when taking this medicine.
This medicine should be used with caution in patients with history of hepatic (liver) impairment, severe renal (kidney) impairment, renal artery stenosis (narrowing of renal arteries), severe cardiac insufficiency, aortic or mitral stenosis (narrowing of heart valves), and angioedema. Monitor potassium levels in elderly.

Disclaimer

Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.

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