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Zibufen 300mg tablet

Brand: Global-Vision
Zibufen 300mg tablet is composed of Dexibuprofen (300mg)

Dexibuprofen is a nonsteroidal anti-inflammatory medicine used to treat moderate to extreme pain, such as menstrual cramps, toothache, and osteoarthritis. Dexibuprofen acts by preventing the action of naturally occurring chemicals in the body known as cyclo-oxygenase (COX) enzymes. These enzymes aid in the production of other compounds in the body known as prostaglandins. By inhibiting the action of COX enzymes, lesser prostaglandins are generated, hence reducing inflammation and pain.


How To Use

The appropriate dose of Dexibuprofen is advised by your doctor. Use the tablets precisely as directed by your doctor.

  • Take Dexibuprofen with food; ideally, at mealtime. This will prevent your stomach from negative effects including stomach discomfort and indigestion. 
  • Swallow the tablet with a glass of water.
  • Swallow the tablet as a whole, do not crush or chew the tablet.
  • If you forget to take a dose, take it immediately when you realize, except when it is almost time for your next dose, in which instance, skip the missed dose and take the next dose in its scheduled time. Do not combine two doses to compensate for a missing dose.

Expert Advice

  • Read the manufacturer's printed instruction sheet from within the packet before starting the therapy. It will offer you with more knowledge about Dexibuprofen as well as a complete list of the negative effects that you may encounter if you take it.
  • Keep Dexibuprofen out of children's and pets' reach.
  • Keep Dexibuprofen away from direct light and heat in a cool, dry place.

Primary Uses


This medicine is used to provide relief from mild to moderate pain experienced in osteoarthritis (bone and joint disease), dysmenorrhoea (painful periods) and for dental pain.

Side Effects

This medicine can cause stomach upset and abdominal pain, dizziness, drowsiness, headache and vertigo (loss of balance). Skin rash is also a side effect that requires immediate stopping of therapy.



Research suggests that this medicine is not safe to be used during pregnancy. Please consult your doctor before taking this medicine.


Research suggests that this medicine is not safe to be used during breastfeeding. Please consult your doctor before taking this medicine.


Patients are recommended to avoid driving if they feel disoriented, drowsy, or weary, or if their eyesight is obscured.


Dexibuprofen has been reported to have a history of causing liver damage. People with liver disorders should consult their doctors before taking Dexibuprofen.  Before beginning treatment, a sample of liver enzymes should be acquired. Consult your doctor if you see any signs of a rise in liver enzymes.


This medicine has been linked to kidney damage. Kidney function must be closely monitored. Dose may need to be altered in kidney disorders. people with kidney disorders should consult their doctors before using Dexibuprofen.


Dexibuprofen should not be taken with alcohol. Symptoms of gastrointestinal bleeding (such as the appearance of dried and brown colored blood in the cough or stools) must be reported to a doctor as soon as possible.


This medicine must be used with caution by patients with history of stomach ulcers and bleeding, alcoholics, mild to moderate kidney and liverdisorders, Crohn's disease, ulcerative colitis, asthma, hypertension and Systemic lupus erythematosus (auto-immune skin disorder). Elderly and long-term therapy patients must be monitored closely.


  • Patients with a known hypersensitivity to Dexibuprofen or nonsteroidal anti-inflammatory (NSAID) medicines should not take it.
  • Contraindicated in people with problems such as rhinitis, urticaria or asthma.
  • Not recommended for people who have had bypass Surgery for the Coronary Artery (CABG)
  • Contraindicated in patients who have just had cardiac surgery.
  • Dexibuprofen is not indicated in individuals with peptic ulcer or other gastrointestinal bleeding problems.


What is Dexibuprofen and how does it work?

It is a Non-steriodal Anti-inflammatory Drug (NSAID) that blocks an enzyme involved in the formation of certain inflammatory mediators of the body that cause pain, stiffness, swelling and fever.

Is this medicine an antibiotic?

No, it is not an antibiotic. It is only a pain killer.

Can this medicine be used to relief headache?

This medicine is mainly used to treat joint pain. It can relieve mild to moderate fever and pain. However, strictly consult your doctor before taking it for any other pains in your body than the one you have been prescribed for.

Can this drug be taken if I have asthma or certain allergies?

No, please do not take this drug if you have asthma or any other allergies. Consult your doctor for further assistance.

Is it safe to use during pregnancy?

No, do not take this drug if you’re pregnant. If you find out that you’re pregnant while taking this medicine then stop the drug immediately and consult your doctor for further assistance.

Is it safe to breast-feed while using this drug?

Studies have shown that this drug is released in breast milk in small amounts. Therefore, its use during breast feeding is discouraged. Please consult your doctor for further assistance.

Can I take this drug with my anti-hypertensive medication?

Dexibuprofen does interact with anti-hypertensive drugs. Please let your doctor know if you’re taking any anti-hypertensive medication and he will guide you accordingly.


Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.


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