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All Purpose Nipple Ointment (APNO) 0.1%/2%/2%

Brand: Nigehban

Prescription Prescription Required

All Purpose Nipple Ointment (APNO) 0.1%/2%/2% others is composed of Betamethasone (0.1%)Mupirocin (2%)Miconazole (2%)

Betamethasone belongs to a group of medicines known as corticosteroids. It works by activating natural substances in the skin to reduce swelling, redness, and itching. Betamethasone is used to treat itching, redness, dryness, scaling, inflammation, and discomfort associated with a variety of skin conditions like psoriasis and eczema. It can also be used to treat rheumatoid arthritis, systemic lupus erythematosus, angioedema, asthma, Crohn’s disease, and dermatitis.


How To Use

  • Betamethasone can be taken by mouth, injected into a muscle, or applied to the skin topically in cream, lotion, or liquid forms.
  • Please follow your doctor’s instructions regarding the dosage and method of administration of betamethasone.
  • Take it at the same time each day to help you remember.
  • Take betamethasone pill with a glass of water.
  • Regarding topical application of betamethasone, follow the instructions given on the label.

Expert Advice

Disocontinue if irritation or burning occur.

Keep this medicine at room temperature. 

Avoid this medicine if you are allergic to it's ingredients. 

Take this medicine at regular intervals as prescribed by your doctor. 

Primary Uses

Allergies, rheumatoid arthritis and systemic lupus erythematosus


  • Betamethasone is used for the treatment of the following conditions:
  • Rheumatoid arthritis
  • Systemic lupus erythematosus
  • Psoriasis
  • Dermatitis
  • Eczema
  • Angioedema
  • Asthma
  • Crohn’s disease
  • Ataxia telangiectasia
  • Phimosis
  • Inflammatory diseases of skin.

Side Effects

  • Some people may experience:
  • Skin atrophy
  • Burning and irritation
  • Hypertrichosis
  • Allergic contact dermatitis
  • Acne
  • Adrenal suppression
  • Cataracts
  • Weight gain
  • Thin fragile skin
  • Small white or red bumps on the skin
  • Swelling, dryness, and redness of skin
  • Decreased resistance to infection
  • Depression.



Risk can not be ruled out, so please consult your doctor before using this medication.


Lactating females should discuss the risks and benefits of using betamethasone with their doctor.


One should not drive a vehicle if using betamethasone induces dizziness, drowsiness, headache, or hypotension.


People that are currently suffering from or have a history of any kind of liver disease should not use betamethasone without doctor’s approval.


There is no harm in consuming alcohol while using betamethasone.


Do not exceed the recommended daily dose. Avoid contact of betamethasone ointment with your eyes, nose, and mouth. Do not use it over large areas of your body. Avoid use in the genital and rectal areas unless asked by a doctor to do so. Do not alter your dosage without a doctor’s approval. Give your doctor your complete medical history especially of untreated infections, liver disease, diabetes, and cushing’s syndrome. Tell your doctor about all the prescription and nonprescription medications that you are taking or plan to take. It is important to tell your doctor that you are taking betamethasone before undergoing any kind of major or minor surgery. Consult your doctor if your condition persists or worsens. Do not use betamethasone cream on your face for more than 5 days.


  • Bethamethasone is contraindicated in people who are allergic to it.
  • Do not use betamethasone if you are suffering from idiopathic thrombocytopenic purpura, a systemic fungal infection, viral infection, active and untreated tuberculosis, and high cholesterol.


How long does it take for this medication to work?

Improvement can be usually noticed within 3 to 4 days.

Are there any major side effects of this medication?

No, there are no major side effects.

Can this medication be used for yeast infection?

Creams containing betamethasone in combination with Clotrimazole may be used to treat yeast infections.

Does this medication make you sleepy?

No, this medication does not make you drowsy.

Can I use this medication if I am pregnant?

The effect of this medication is undetermined in pregnant females, therefore; be cautious. Consult your healthcare provider.

Can I use this medication to treat viral and fungal infections?

No, this medication does not treat viral and fungal infections.

What is the use of this medicine?

It is an antibiotic topical which prevents the bacterial growth on skin. It will treat infections like impetigo, Staph infection.

How quickly will Mupirocin work?

You will start noticing the skin getting better within few days. However, if that doesn’t happen after 4 to 5 days then consult your doctor.

What bacteria does this medicine destroy?

It will help in killing the bacterial strains like Staphylococcus aureus and Streptococcus pyogenes. It stops bacteria from multiplying.

Is this medicine same as neosporin?

As compared to the OTC first aid topical antibiotics, Mupirocin will help kill large variety of bacteria and a good alternative in case if one is allergic to certain ingredients of OTC products.

Is Mupirocin ointment a steroid?

Mupirocin cream is basically a RNA synthetase inhibitor antibiotic.

What are the uses of Miconazole?

This medication is used for treating fungal infections such as athlete’s foot, ringworm, jock itch, and other fungal skin infections (candidiasis). It can also be used to treat a skin condition known as Pityriasis (tinea versiolor) characterized by shedding of parts of skin as flaky scales.

How to take Miconazole?

Use it as prescribed by your health care provider. Make sure to complete the course of the medication. If you stop using the medicine before the prescribed time, the fungus may grow back and worsen the condition. The dosage of this medicine is dependent on the age, condition, and its severity.

How to store Miconazole?

Different brands of the medicine have different storage instructions. Keep medicine away from excessive light, moisture, and children. In case of gel form, keep medicine away from flame. Please do not flush medicines down the toilet. Please read the leaflet provided with the medicine for further storage guidance.

Will this medicine cause scars?

This medicine is unlikely to leave scars. However, scar formation is also dependent on the fungus type and the patient’s skin. For further guidance, consult your healthcare provider.

Can I use Miconazole to treat my acne?

There are several types of acne. One type of acne may be treated with Miconazole but consultation by a skin professional is must.

Does Miconazole have any effect on pregnancy and lactation?

This medicine should only be used during pregnancy if it is necessary and no safer alternate is available. The effects of this medicine on lactating mothers are unknown. Consult your health care provider before use of this medicine.

Important notes for use of Miconazole.

• Please do not share this medicine with anyone. • If you use this medicine for Pityriasis, it may take several months for the skin to grow back to its normal condition/ appearance.


Dawaai's intention is to make sure that it's consumers get information that is accurate, reviewed by an expert and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, which may not cover all possible precautions, side effects, contraindications or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.


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