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Hyperlipidemia

Description

Cholesterol is a type of fat in the blood that is essential for normal functioning of the cells, nerves, and hormones, but if it exceeds the normal limits it becomes harmful. Increased level of cholesterol in the body is known as hyperlipidemia.

Following are the different types of cholesterol in our body:

  • LDL (low-density lipoprotein): It is the bad kind of cholesterol that carries and deposits the fat along the walls of arteries causing them to become hard and narrower.
  • HDL (high-density lipoprotein): It is the good kind of cholesterol that carries the extra fat to the liver without depositing them along the walls of the arteries. It helps lower the risk of heart attacks.
  • Triglycerides: It stores and transports fat in the blood. Excess calories (especially sugar and alcohol) are stored this way.

Hyperlipidemia or hyperlipoproteinemia is a very common disorder characterized by abnormally increased levels of lipoproteins or lipids in the blood. Lipoproteins are molecules made up of lipids and proteins. The two common types of lipids are triglycerides and cholesterol, therefore; it is also commonly called hypercholesterolemia and hypertriglyceridemia. It is a major risk factor for heart diseases. It has two subtypes:

  1. Primary or familial hyperlipidemia
  2. Secondary or acquired hyperlipidemia.
Causes
  • Primary hyperlipidemia:

Primary hyperlipidemia or familial hyperlipidemia results from genetic abnormalities. It runs in families; you may have it if your parents or siblings have it.

 

  • Secondary hyperlipidemia:

Secondary hyperlipidemia or acquires hyperlipidemia is caused by:

 

  1. Diet rich in cholesterol and fats
  2. Sedentary lifestyle
  3. Medicines such as thiazides, beta-blockers, and estrogen
  4. Hypothyroidism
  5. Pregnancy
  6. Kidney disease
  7. Alcohol abuse

 

Risk factors

PREVENTABLE:

  • Smoking
  • Alcohol
  • Unhealthy diet (eating foods such as full-fat dairy products, meat and processed food)
  • Sedentary lifestyle (lack of physical exercise)

NON PREVENTABLE:

  • Hypertension (high blood pressure)
  • Diabetes
  • Hypothyroidism (underactive thyroid gland)
  • Polycystic ovarian disease
  • Pregnancy

 

Symptoms

Hyperlipidemia usually presents with no signs and symptoms but puts you at a greater risk of developing other medical illnesses:

  • High blood pressure (fat starts to build up along the walls of the arteries which causes them to become narrower that might shoot up the blood pressure)
  • Heart attack (fat build-up may form a blood clot that might travel to the heart and cause a heart attack)
  • Stroke
  • Diabetes
  • Xanthelasma (in rare cases high cholesterol may start getting deposited around eyes)
Diagnosis

To reach a diagnosis, your doctor will ask for your complete medical history and perform a simple physical exam. To confirm the diagnosis your doctor will recommend blood test called lipid profile for levels of:

  1. LDL or bad cholesterol
  2. HDL or good cholesterol
  3. Total cholesterol
  4. Triglycerides
Management

The goal of management is to maintain normal lipid values to avoid risk of heart diseases. It includes:

  1. Lifestyle modification: Your doctor will recommend you to follow a strict diet, avoid alcohol, quit smoking, and add exercise to your daily routine.

 

 

  1. Medicines:
  • Statins (lipid-lowering medicines): Atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, and rosuvastatin
  • Cholestyramine and colestipol
  • Gemfibrozil, fenoglide, and triglide
  • Niacin
  • Asezetimibe.
When to consult a doctor?

A medical professional should be consulted right away if one feels a sudden chest pain, shortness of breath, dizziness, numbness, slurred speech and difficulty in walking.

 

Available Medicine for Hyperlipidemia

Lipiget 10 mg

Rs.245

Getz Pharma

Lipiget 20 mg

Rs.455

Getz Pharma

Lipiget 40 mg

Rs.570

Getz Pharma

Lipitor 10mg

Rs.350

Pfizer

Lipitor 20mg

Rs.1128.6

Pfizer

Stat-A 20mg

Rs.170

High-Q

Lipirex 10mg

Rs.200

Lowitt

Pro-statin 20mg

Rs.350

CCL

Atorva 10mg

Rs.280

Pharmatec

Lipitor 40mg

Rs.2019.6

Pfizer

Lastolip 20mg

Rs.300

Wilshire

Lochol 10mg

Rs.194.85

Scilife

Lipirex 20mg

Rs.400

Highnoon

Stat-A 40mg

Rs.230

High-Q

Stat-A 10mg

Rs.126

High-Q

Lipiget EZ 10 mg / 10 mg

Rs.275

Getz Pharma

Lipirex 40mg

Rs.450

Highnoon

Atorva 40mg

Rs.551.93

Pharmatec

Descol 20mg

Rs.360

Marvi

Descol 10mg

Rs.198

Marvi

Oscar 10mg

Rs.180

Scotman

Oscar 20mg

Rs.170

Scotman

Oscar 40mg

Rs.600

Scotman

Oscar Plus 5mg/10mg

Rs.200

Scotman

Oscar Plus 5mg/20mg

Rs.287

Scotman

Jezeta 10mg/40mg

Rs.495

Hilton

Jezeta 10mg/10mg

Rs.290

Hilton

Tavist 10mg

Rs.167.16

Macter

Jezeta 20mg/10mg

Rs.455

Hilton

Lipivastin 10mg

Rs.100

Mass-PH Health

Lastolip 10mg

Rs.180

Wilshire

Atorva 20mg

Rs.498.73

Pharmatec

Lipotrim 20mg

Rs.350

Maple

Winstor 10mg

Rs.184

Sanofi

Winstor 20mg

Rs.282.98

Sanofi

Winstor 40mg

Rs.549

Sanofi

Am-Descol 10/10mg

Rs.181.06

Nabi Qasim

Sensicon 10 mg

Rs.210

Barrett

Orva 20mg

Rs.360

Bosch

Orva 10mg

Rs.200

Bosch

AM-Descol 5/10 mg

Rs.175

Marvi

Gempid 600mg

Rs.114.33

Atco

Pitalo 2mg

Rs.300

Genix

Pitalo 4mg

Rs.350

Genix

Pitalo 1mg

Rs.150

Genix

Rovista 5 mg

Rs.185

Getz Pharma

Rovista 10 mg

Rs.338.97

Getz Pharma

Rovista 20mg

Rs.475

Getz Pharma

X-plended 20mg

Rs.476

Pharm Evo

X-plended 10mg

Rs.289.67

Pharm Evo

X-plended 5mg

Rs.185

Pharm Evo

Omnitor 5mg

Rs.165

Macter

Omnitor 10mg

Rs.290

Macter

Omnitor 20mg

Rs.430

Macter

Rolip 10mg

Rs.290

Hilton

Rolip 20mg

Rs.485

Hilton

Vaptor 10mg

Rs.264

Searle

Xovat 5mg

Rs.165

Aspin Pharma

Xovat 10 mg 10's

Rs.269

Aspin Pharma

Xovat 20mg

Rs.425

Aspin Pharma

Rosubar 20mg

Rs.449

Barrett

Rosubar 5mg

Rs.149.37

Barrett

Loster 5 mg

Rs.150

Helix Pharma

Vaptor 20mg

Rs.470.81

Searle

Rosuvax 10mg

Rs.259.99

Asian Continental

Roviros 5mg

Rs.275

Marvi

Rosubar 10mg

Rs.289.7

Werick

Loster 20mg

Rs.400

Helix Pharma

Rast 5 mg 5mg

Rs.180

Tabroos

Kestore 10mg

Rs.149.9

Scilife

Crestat 20mg

Rs.484.5

CCL

Crescor 20mg

Rs.350

Martin Dow Marker

Fortius 5mg

Rs.144

High-Q

Aurora 10mg

Rs.277

Ferozsons

Rolip 5mg

Rs.188

Hilton

Aurora 5mg

Rs.150

Ferozsons

Aurora 20mg

Rs.425

Ferozsons

Rosulin 10mg

Rs.290

Highnoon

Rosulin 20mg

Rs.460

Highnoon

Cougar 10mg

Rs.229

Scotman

Cougar 20mg

Rs.375

Scotman

Cougar 5mg

Rs.138

Scotman

Fortius 10mg

Rs.240

High-Q

Rovator 5 mg

Rs.175.32

Atco

Neostat 10 mg

Rs.199

Soin Pharma

Rosulin 5mg

Rs.148.12

Highnoon

Crestat 10 mg 10mg

Rs.295.8

CCL

Rast 20 mg 20mg

Rs.470

Tabroos

Vaptor 5mg

Rs.169

Searle

Rosuvax 5mg

Rs.159.99

Asian Continental

Rast 10mg 10mg

Rs.280

Tabroos

Loster 10mg

Rs.250

Helix Pharma

ROVATOR 10 mg

Rs.288.89

Atco

Rosuva 5mg

Rs.177.44

Wilson's

Crestat 5mg 5mg

Rs.185

CCL

Staars 20mg

Rs.350

Horizon Pharma

Kestore 20mg

Rs.249.9

Scilife

Qazzo 20mg

Rs.400

Wilshire

Rosuva 10mg

Rs.289.68

Wilson's

Crescor 10mg

Rs.200

Martin Dow Marker

Rosca 10 mg

Rs.280

Genix

Crescor 5 mg

Rs.120

Martin Dow Marker

Rosera 20 mg

Rs.395

Sami

Rolip Eze 5 mg / 10 mg

Rs.235

Hilton

Rolip Eze 10 mg / 10 mg

Rs.340

Hilton

Rolip Eze 20 mg / 10 mg

Rs.510

Hilton

Cougar 10 mg

Rs.266.66

Scotmann

Rova 20mg

Rs.421

Bosch

Xenecor 20mg

Rs.469

ICI Pakistan Limited

Xenecor 5mg

Rs.147

ICI Pakistan Limited

Rova 5mg

Rs.140

Bosch

Xenecor 10mg

Rs.245

ICI Pakistan Limited

Rovator 20mg

Rs.420

Atco

Rovista EZ 5 mg / 10 mg

Rs.323

Getz Pharma

Rovista EZ 20 mg / 10 mg

Rs.648

Getz Pharma

Recol 10mg

Rs.226.55

Barrett

Recol 20mg

Rs.357.26

Barrett

Survive 10mg

Rs.170

Werick

Survive 20mg

Rs.320

Werick

Zocor 10mg

Rs.336.96

OBS

Zocor 20mg

Rs.646.17

OBS

Zocor 40mg

Rs.1010.88

OBS

Simbex 20mg/10mg

Rs.350

Searle

Simbex 10mg/10mg

Rs.300

Searle

Neocom S 10 mg/ 10 mg

Rs.208

novins

Simva 10mg

Rs.193.83

Marvi

Simvazaf 20 mg

Rs.205.8

Zafa

Simvazaf 20 mg

Rs.220.2

Zafa

Simvazaf 10mg

Rs.123.86

Zafa